TMJ Pain
Conditions
Brief summary
Randomized clinical trial between 2groups,the study group to be injected in the TMJ with injectable platelet rich fibrin with vitamin C and the control group to be injected in the TMJ with injectable platelet rich fibrin alone in management of internal Temporomandibular joint derangement
Detailed description
Randomized clinical trial between 2groups,the study group to be injected in the TMJ with injectable platelet rich fibrin with vitamin C and the control group to be injected in the TMJ with injectable platelet rich fibrin alone in management of internal Temporomandibular joint derangement
Interventions
DRUGVitamin C
addition of vitamin C to IPRF
injection of IPRF alone
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
Patients with internal TMJ derangement (anterior disc displacement with reduction)
Exclusion criteria
Pathological conditions ; trauma TMJ cases or any blood diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain management | at 4;8;12;16 weeks | Evaluation of pain using VAS pre and post injections |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| disc position using MRI | at 4;8;12;16 weeks | evaluation of disc position pre and post injections |
Other
| Measure | Time frame | Description |
|---|---|---|
| maximum mouth opening | at 4;8;12;16 weeks | measurement of MMO using digital caliper pre and post injections |
| lateral excursion | at 4;8;12;16 weeks | measurement of lateral excursion using digital caliper pre and post injections |
Countries
Egypt
Outcome results
None listed