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Volume Outcome Relationships and Effects

Volume Outcome Relationships and Effects of Adjuvant and Neoadjuvant Therapy in Mortality in Esophageal Cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06343597
Enrollment
30
Registered
2024-04-02
Start date
2020-06-15
Completion date
2028-06-15
Last updated
2026-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Cancer

Brief summary

This is a retrospective analysis to assess if high-volume hospital facilities experience greater or lesser rates of incidence in patients with esophageal cancer than low-volume facilities.

Detailed description

This is a retrospective analysis to assess if high-volume hospital facilities experience greater or lesser rates of incidence in patients with esophageal cancer than low-volume facilities. The relationship between volume and outcomes has been proven in pancreatic cancer. Similar to pancreatic cancer, esophageal cancer historically has a bad prognosis. Esophageal cancer is typically asymptomatic, resulting in an advanced stage at the time of diagnosis. Additionally, it also has a significantly high morbidity and mortality. Therefore, it is crucial to determine volume-outcome relationships in esophageal cancer. This study aims to elucidate what these findings may entail by evaluating the impact that the volume-outcome relationship has on treatment assessment in esophageal cancer patients. The purpose of the study is to evaluate the outcomes of esophageal cancer resection in patients in high volume (more than 5 esophagectomy performed per year) and low volume (less than 5 esophagectomy performed per year) hospital facilities. Furthermore, this paper will assess the outcomes of neoadjuvant and adjuvant therapy in esophageal cancer.

Interventions

None listed

Sponsors

Methodist Health System
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* esophageal cancer

Exclusion criteria

* No esophageal cancer

Design outcomes

Primary

MeasureTime frameDescription
Esophageal Cancer resection in patients in high volume (more than 5 esophagectomy performed per year) and low volume (less than 5 esophagectomy performed per year) hospital facilitiesthrough study completion, up to 18 monthsRetrospective analysis to assess if high-volume hospital facilities experience greater or lesser rates of incidence in patients with Esophageal Cancer than low-volume facilities

Countries

United States

Contacts

CONTACTCrystee Cooper, DHEd
clinicalresearch@mhd.com214-947-1280
CONTACTZaid Haddadin, MS
clinicalresearch@mhd.com214-947-1280
PRINCIPAL_INVESTIGATORDhiresh Jeyarajah, MD

Methodist Health System

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 21, 2026