Cognitive Performance
Conditions
Brief summary
This is a 2 x 2-factor crossover design study to investigate the effects of time of day and nuts on post-meal cognitive performance.
Detailed description
In this trial, eligible participants will receive isocaloric meals with or without nuts at lunchtime and dinner time. Cognitive performance will be performed before and 90 min after the meals.
Interventions
OTHERNuts
Isocaloric meal with nuts
OTHERNut-free meal
Isocaloric meal without nuts
Sponsors
Monash University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE
Intervention model description
2 x 2-factor crossover design study
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Non-shift workers * 18-55 years * BMI between 18.5 and 27 kg/m2, * Non-smokers * Without chronic illnesses
Exclusion criteria
* Allergy to nuts * BMI\<18.5 or \>27 kg/m2 * Presence of dementia or psychiatric disease (depression, Parkinson's disease, schizophrenia) * Presence of diabetes, serious health conditions that may affect participation e.g. liver or thyroid dysfunction, recent major surgery, cardiovascular disease * Presence of any sleep disorders * Taking anti-diabetic or lipid-lowering medication * Do not speak English * Pregnant or planning on becoming pregnant * Breastfeeding
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| N-back task - accuracy | before meal x 90 min post-meal | Difference in the total accuracy |
| N-back task - matched responses | before meal x 90 min post-meal | Difference in the % matched responses |
| N-back task - false alarm | before meal x 90 min post-meal | Difference in the % false alarm |
| N-back task - reaction time | before meal x 90 min post-meal | Difference in the reaction time for correct matched responses |
| Stroop test - congruent | before meal x 90 min post-meal | Difference in the reaction time for congruent |
| Stroop test - incongruent | before meal x 90 min post-meal | Difference in the reaction time for incongruent |
| Stroop test - interference | before meal x 90 min post-meal | Difference in stroop interference (incongruent - congruent response time) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Multitasking - pure blocks | before meal x 90 min post-meal | Difference in the reaction time for pure blocks |
| Satiety index | Satiety index will be assessed before the meal and 4 times after the meal (15, 30, 60 and 90 mins). | Difference in postprandial satiety index, calculated using the mean of the four satiety questions, where hunger and eating capacity will be scored in an inverse way than fullness and satisfaction. |
| Multitasking - mixed blocks | before meal x 90 min post-meal | Difference in the reaction time for mixed blocks |
| Multitasking - mixing cost | before meal x 90 min post-meal | Difference in mixing cost (mixed - pure reaction time) |
| Satiety - hunger | Hunger will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). | Difference in postprandial hunger |
| Satiety - fullness | Fullness will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). | Difference in postprandial fullness |
| Satiety - satisfaction | Satisfaction will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). | Difference in postprandial satisfaction |
| Satiety - eating capacity | Eating capacity will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). | Difference in postprandial eating capacity, |
Countries
Australia
Outcome results
None listed