Colorectal Cancer, ERAS
Conditions
Brief summary
The Enhanced Recovery after Surgery (ERAS) protocol has transformed perioperative care, representing a significant paradigm shift in managing colorectal cancer patients. While the immediate benefits of Enhanced Recovery After Surgery (ERAS) in expediting postoperative recovery are well-documented and widely acknowledged, it is essential to investigate its long-term implications, particularly its influence on survival rates. The aim of this study will be to analyse the impact of compliance with the ERAS protocol on long- term outcomes after laparoscopic colorectal resection.
Detailed description
The aim of this study will be to analyse the impact of compliance with the ERAS protocol on long- term outcomes after laparoscopic colorectal resection. The study will be designed as a prospective observational study to compare the long-term effects of surgical treatment of colorectal cancer in two groups of patients: those with high compliance with the ERAS protocol (≥80%) and those with low compliance with the ERAS protocol (<80%). The primary outcome of the study will be the 5-year survival rate. The inclusion criteria for Group 1 will involve 128 patients with ERAS compliance below 80%. Conversely, Group 2 will consist of 340 patients, all of whom achieved a compliance rate of at least 80%. The correlation between compliance with the ERAS protocol and 5-year survival will be assessed using the Kaplan-Meier method with log-rank tests. Additionally, survival analysis will be conducted separately for groups with varying cancer stages.
Interventions
Patients were categorized into two groups based on their adherence to the ERAS protocol: group 1 with a compliance rate below 80% and group 2 with a compliance rate of 80% or above.
Sponsors
Study design
Eligibility
Inclusion criteria
* patients undergoing treatment for colorectal cancer
Exclusion criteria
* primary open or emergency surgery, * transanal endoscopic microsurgery (TEM), * stage IV of the disease according to the American Joint Committee on Cancer (AJCC) classification, * multivisceral resection, * concomitant inflammatory bowel diseases, * intensive care unit stay immediately after surgery * lost-to-follow-up patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post operative 5 year survival rate | 5 years |
Countries
Poland