Skip to content

PENG and LFCN Block Versus FIC Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis Focused on Movement (Retro-PvF)

Pericapsular Nerve Group (PENG) Block and Lateral Femoral Cutaneous Nerve (LFCN) Block Versus Fascia Iliaca (FIC) Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis Focused on Movement (Retro- PvF)

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06342102
Acronym
Retro-PvF
Enrollment
80
Registered
2024-04-02
Start date
2024-03-26
Completion date
2024-04-30
Last updated
2025-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Regional Anesthesia, Regional Anesthesia Block, Total Hip Arthroplasty \(THA\), Total Hip Replacement Surgery

Keywords

PENG, LFCN, fascia iliaca, THA, total hip replacement surgery, analgesia, movement, Peripheral nerve blocks

Brief summary

Total hip arthroplasty is a major surgical procedure performed on a growing number of patients. Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation, thus expediting hospital discharge. Amongst the many peripheral nerve blocks, FIB (fascia iliaca block) has been recommended as the block of choice by many international guidelines since it offers the best pain control with a relatively low risk of motor block. PENG (pericapsular nerve group) and its association with LFCN (lateral femoral cutaneous nerve) has been proposed as an effective alternative that offers comparable, If not better, pain control with a considerably lower risk for motor block compared to FIB. Given the novelty of this block, there are few published papers on the subject, mostly case series or case reports thus justifying the need for retrospective study.

Detailed description

The primary outcome was the degree of residual quadriceps femoris muscle paresis assessed with the MRC (medical research council) scale at 6 hours between PENG and LCFN. The secondary outcomes were NRS (numeric rating scale) at 6,12, 24 hours, total opioid consumption expressed as milligrams of morphine equivalents (MME), time to first rescue opioid and time to first postoperative ambulation.

Interventions

The PENG block was performed under ultrasound guidance. After skin disinfection, the needle was advanced between the psoas tendon and pubic ramus where 20 mL of 0.5% ropivacaine were injected. The LFCN block was performed following the PENG block.10 ml of 0.5% ropivacaine were injected near the nerve into the fat-filled flat tunnel (FFFT) located at the level of the superior anterior iliac spine and lateral to the sartorius muscle.

PROCEDUREFIC block

FICB was performed under ultrasound guidance. The needle was advanced above the fascia iliaca and 20 mL of 0.5% ropivacaine were injected

Sponsors

Ospedale Edoardo Bassini
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* elective total hip replacement surgery for non-traumatic hip disease, * age over 18 years, * complete clinical chart including type of peripheral nerve block performed, * signed consent form for spinal anesthesia and peripheral nerve block.

Exclusion criteria

* preoperative opioid therapy, * having received a peripheral nerve block other than PENG + LFCN or FICB, * having received general anesthesia, * incomplete chart, * documented muscle weakness * deviation from the established post-operative analgesia protocol.

Design outcomes

Primary

MeasureTime frameDescription
Movement of the lower limb affected by surgery6 hours after surgeryThe Medical Research Council (MRC) Muscle Strength Scale (ranging scale from 0 to 5 0= no visible contraction, 5=normal power) was used to assess the degree of residual quadriceps femoris muscle paresis 6 hours postoperatively.

Secondary

MeasureTime frameDescription
pain control6 hours after surgerypain assessment with Numeric Rating Scale (NRS): a 0-10 scale, with zero meaning no pain and 10 meaning the worst pain imaginable
Morphine Milligram Equivalents (MME) of pro re nata (PRN) opioid doses24 hours after surgerywe studied the effect of Regional anesthesia on opioid-sparing

Other

MeasureTime frameDescription
time to first opioid requestFrom date of surgery until up to 3 days afterwe studied the effect of Regional anesthesia on opioid-sparing
time to first postoperative ambulationFrom date of surgery until up to 3 days afterwe studied the effect of Regional anesthesia on opioid-sparing

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026