Single-stage ERCP and Laparoscopic Cholecystectomy for Cholecystocholedocholithiasis: Which to Start With?

Single-stage Endoscopic Retrograde Cholangiopancreatography and Laparoscopic Cholecystectomy for Cholecystocholedocholithiasis: Which to Start With?

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06340594

Enrollment

115

Registered

2024-04-01

Start date

2021-01-01

Completion date

2024-01-30

Last updated

2024-04-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biliary Stones, Choledocholithiasis With Cholecystitis

Keywords

Choledocholithiasis, ERCP, Laparoscopic cholecystectomy, Cholecystocholedocholithiasis

Brief summary

Chronic calculous cholecystitis is associated with common bile duct (CBD) stones in approximately 12% of patients. These patients need both cholecystectomy and CBD clearance of stones. The standard for cholecystectomy is laparoscopic cholecystectomy (LC) and the mostly common treatment used for CBD clearance is Endoscopic Retrograde Cholangiopancreatography (ERCP). The two interventions can be combined to be done at the same time under single anesthesia session. Studies of single stage ERCP+LC showed confirmed the safety and efficacy of the combined technique. However, some surgeons start with the ERCP while others start with LC.The aim of this study is to compare the start with ERCP followed by LC to the start with LC followed by ERCP when the two techniques are combined at the same session for treatment of chronic calculous cholecystitis associated with CBD stones regarding efficacy and safety of the two approaches.

Interventions

PROCEDURELaproscopic cholecystectomy (LC)

Removal of gallbladder via laparoscopy

PROCEDUREEndoscopic Retrograde Cholangiopancreatography (ERCP)

Removal of bile duct stones via endoscopy

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Inclusion criteria

* Patients underwent single stage ERCP+LC for cholecystocholedocholithiasis

Exclusion criteria

* Contraindications to ERCP, or laparoscopic surgery * Cholangitis and pancreatitis * Previously failed ERCP

Design outcomes

Primary

Measure	Time frame	Description
Operative time operative time	time in minutes from intubation of the patient to the end of procedure	total operative time of both ERCP+LC

Secondary

Measure	Time frame	Description
CBD clearance rate	up to 2 years	success rate of retrieval of stones
Length of hospital stay	up to 2 weeks post-operative	days of hospital stay
Mortality rate	up to 1 month postoperative	number of deaths intraoperative and postoperative related to surgery

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026