Dyslipidemias
Conditions
Brief summary
To evaluate the effects of a nutraceutical containing Berberine-based Food Supplement, Artichoke Extract, Phytosterols, Fenugreek and SelectSIEVE® OptiChol on lipid profile
Detailed description
To evaluate the effects of a nutraceutical containing Berberine-based Food Supplement, Artichoke Extract, Phytosterols, Fenugreek and SelectSIEVE® OptiChol compared to placebo on lipid profile in patients with LDL cholesterol \> 115 and \< 190 mg/dl.Patients were allocated to receive 1 or 2 tablets of the nutraceutical for 12 weeks.
Interventions
DIETARY_SUPPLEMENTBerberine-based Food Supplement, Artichoke Extract, Phytosterols, Fenugreek and SelectSIEVE® OptiChol
Patients will take 1 tablet of Berberine-based Food Supplement, Artichoke Extract, Phytosterols, Fenugreek and SelectSIEVE® OptiChol for 12 weeks
Sponsors
Fondazione IRCCS Policlinico San Matteo di Pavia
University of Pavia
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* LDL Cholesterol \> 115 mg/dl and \< 190 mg/dl * primary prevention
Exclusion criteria
* patients with neoplastic and liver diseases, renal failure and diabetes mellitus * pregnant or breastfeeding women * hypersensitivity to any of the ingredients * therapy with lipid-lowering drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Variations of lipid profile | 12 weeks |
Countries
Italy
Contacts
Primary ContactGiuseppe Derosa
Outcome results
None listed