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The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters.

The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06340061
Enrollment
80
Registered
2024-04-01
Start date
2022-10-20
Completion date
2024-12-31
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Brief summary

The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared. Additionally, an investigation was conducted to explore the relationship between anterior chamber parameters, corneal biomechanics, and the severity of glaucoma

Interventions

OTHERObservational study

The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared. Additionally, an investigation was conducted to explore the relationship between anterior chamber parameters, corneal biomechanics, and the severity of glaucoma

Sponsors

Henan Provincial People's Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
22 Years to 79 Years
Healthy volunteers
Yes

Inclusion criteria

* Clinical diagnosis of primary glaucoma. * Must be able to cooperate to complete the inspection.

Exclusion criteria

* Secondary glaucoma. * Corneal disease (E. g., keratitis, corneal scarring) that the investigator believes may affect the examination. * trauma * congenital eye malformations

Design outcomes

Primary

MeasureTime frameDescription
IOPthrough study completion, an average of 2 years.Intraocular pressure
bIOPthrough study completion, an average of 2 years.Biomechanical intraocular pressure. Corneal Biomechanics Parameters.
ACDthrough study completion, an average of 2 years.Anterior chamber depth. Anterior Chamber Parameters.
ACWthrough study completion, an average of 2 years.Anterior chamber width. Anterior Chamber Parameters.
SSIthrough study completion, an average of 2 years.Stress-strain index. Corneal Biomechanics Parameters.
VFthrough study completion, an average of 2 years.visual field. The severity of glaucoma is mainly based on the damage of the visual field

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026