Postoperative New-onset Proteinuria and Adverse Outcomes.

Association Between Postoperative New-onset Proteinuria and Adverse Outcomes: a Retrospective Cohort Study.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06339229

Enrollment

2983899

Registered

2024-04-01

Start date

2000-01-01

Completion date

2023-11-01

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mortality, Proteinuria, Surgery

Brief summary

We aimed to assess the association between postoperative new-onset proteinuria, all-cause mortality, and decline in kidney function in Chinese people who underwent surgery. The exposure variable was the dipstick proteinuria values from the initial postoperative urinalysis within 30 days after surgery, categorized as negative, trace, 1+, and ≥2+. The primary outcome was 30-day mortality. The secondary outcomes included 1-year mortality and composite kidney outcome assessed using the postoperative estimated glomerular filtration rate.

Interventions

OTHERproteinuria

dipstick proteinuria values negative, trace, 1+, and ≥2+

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

16 Years to No maximum

Healthy volunteers

Inclusion criteria

* surgery patients

Exclusion criteria

* kidney or urinary surgery * missing urinalysis results * dipstick proteinuria indicated a value of ≥ trace at least once preoperatively * with dialysis, end-stage renal disease, or with urinary tract infection at baseline * missing follow-up information

Design outcomes

Primary

Measure	Time frame
mortality	30-day

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026