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CT-based Model for Predicting Prolonged Weaning in Patients With Abdominal Trauma

CT-based Model for Predicting Prolonged Weaning From Mechanical Ventilation in Patients With Abdominal Trauma: a Retrospective Cohort Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06339073
Enrollment
1023
Registered
2024-04-01
Start date
2023-10-01
Completion date
2024-02-05
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilation Therapy; Complications, Wounds and Injuries

Keywords

computed tomography, prolonged weaning, ventilation, trauma

Brief summary

Critically ill patients often require tracheal intubation for mechanical ventilation, and timely weaning is crucial for airway management and reducing complications. However, there is currently a lack of an effective tool to predict weaning time in critically ill patients. This retrospective study established an effective nomogram model for predicting the time of weaning from mechanical ventilation in abdominal trauma patients by considering multiple perspectives. The model has been validated and demonstrated good performance in terms of discrimination, calibration, and clinical utility. Moreover, the model can effectively predict the prognosis of critically ill patients. The findings of this study have important implications for guiding respiratory management in clinically critically ill patients, particularly trauma patients.

Interventions

DEVICEmechanical ventilation

Abdominal trauma patients were treated with mechanical ventilation according to their conditions.

Sponsors

Jinling Hospital, China
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* (1) with information on survival status and time; * (2) aged 18-80 years; * (3) admitted to ICU; * (4) with abdominal CT performed within 1-week post-trauma; * (5) use of mechanical ventilation.

Exclusion criteria

* (1) low-quality CT images; * (2) history of mental illness.

Design outcomes

Primary

MeasureTime frameDescription
Prolonged mechanical ventilationthrough whole hospitalization of each participant, an average of 25 daysProlonged mechanical ventilation was defined as length of mechanical ventilation \>7 days

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026