Coronary Artery Disease, Hyperlipidemias
Conditions
Keywords
Percutaneous coronary intervention, Statin
Brief summary
For the management of low-density lipoprotein-cholesterol (LDL-C), some guidelines recommend initial statin treatment with high-intensity statins to achieve at least a 50% reduction in LDL-C levels. High-intensity or maximally tolerated intensity can be maintained without a target goal. However, the European guideline recommends less than 55 mg/dL of LDL-C after PCI.
Detailed description
To investigate the Optimal Attained LDL-C Levels in Patients Who Achieved ≥50% LDL-C Reduction After PCI.
Interventions
DRUGLDL reduction therapy
LDL reduction therapy
Sponsors
Samsung Medical Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients receiving PCI with health check up before and after PCI within 3 years
Exclusion criteria
* Patients receiving statin before PCI * Patients with liver cirrhosis * Patients with cancer * Patients without prescription of statin * Patients with LDL-C \<55 mg/dL before PCI
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MACCE | 10 years after PCI | major adverse cardiac and cerebrovascular events |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cardiovascular death | 10 years after PCI | death from cardiovascular cause |
| Spontaneous myocardial infarction | 10 years after PCI | MI with hospitalziation |
| Repeat revascularization | 10 years after PCI | additional PCI or CABG |
| Ischemic stroke | 10 years after PCI | Stoke from ischemic cause |
Countries
South Korea
Outcome results
None listed