Cardiovascular Disease, Type 2 Diabetes Mellitus
Conditions
Brief summary
The association between Cardiovascular Disease (CVD) and Chronic Kidney Disease (CKD) is well established. Traditional risk factors for CVD and CKD are similar, with type 2 diabetes mellitus (T2DM) being the most prevalent risk factor. However, CKD is underdiagnosed and undertreated in patients with CVD. Further understanding of the combination of CKD in CVD patients is important to formulate prevention and treatment strategies for CVD patients and high-risk groups, reduce adverse events in CVD patients, and prevent progression of CKD to End Stage Renal Disease (ESRD).
Detailed description
The PLACARD study will include approximately 3,000 patients presenting to the cardiology department with type 2 diabetes and cardiovascular disease. The aim of this study was to assess the prevalence of proteinuria (urinary ACR) in type 2 diabetic patients with different cardiovascular diseases, both inpatient and outpatient in the cardiology departments of secondary and tertiary hospitals in China. Participants will be recruited at 30 clinical centers for a period of six months.
Interventions
None listed
Sponsors
Beijing Anzhen Hospital
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥18 years old; * Diagnosed T2DM combined with ≥1 CVD (hypertension, coronary heart disease, atrial fibrillation, heart failure); * During the data collection period, they went to the outpatient clinic of the cardiology department of the research center, or received treatment in the cardiology department; * Ability to self-sign informed consent (electronic /paper).
Exclusion criteria
* Pregnant or lactating women; * Dialysis patients; * Other diseases that lead to elevated albuminuria, such as severe infection, confirmed primary glomerular disease, etc.; . Malignant tumors being treated (surgery, chemotherapy, radiotherapy or targeted therapy); * Cachexia (CSS score ≥ 5 points); * Severe liver disease (Child- Pugh grade C) ; * Participated in an interventional clinical trial in the past three months.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The prevalence of albuminuria | On the day of patients enrollment. | To assess the prevalence of albuminuria in patients who are combined with type 2 diabetes mellitus and different cardiovascular diseases in inpatient and outpatient cardiology departments of secondary and tertiary hospitals in China. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Lthe prevalence of microalbuminuria and macroalbuminuria evels of microalbuminuria and macroalbuminuria | On the day of patients enrollment. | To evaluate the levels of microalbuminuria and macroalbuminuria of patients with type 2 diabetes mellitus (T2DM) in inpatients and outpatients cardiology departments; |
| The prevalence of microalbuminuria and macroalbuminuria | On the day of patients enrollment. | To evaluate the prevalence of microalbuminuria and macroalbuminuria in patients with T2DM complicated with different cardiovascular diseases |
| To evaluate the related influence factors of albuminuria and the treatment patterns of CKD patients and non-CKD patients in cardiology departments; | On the day of patients enrollment. | After outpatient patients receive feedback on their renal function tests, assess whether physicians prescribe new relevant medical orders by recording them. Evaluate the treatment patterns for CKD and non-CKD patients in the cardiology department. |
| Evaluate the management of patients with type 2 diabetes mellitus and cardiovascular disease across different levels of cardiology departments in hospitals. | On the day of patients enrollment. | Collect clinical assessment data from patients (including test results and the frequency of these tests over the past year), and assess the management of patient-related risk factors and complications by physicians in hospitals of different levels based on the frequency of testing. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Exploratory Objective | On the day of patients enrollment. | To evaluate the prevalence of retinopathy in T2DM patients with different cardiovascular diseases attending inpatient and outpatient cardiology departments in secondary and tertiary hospitals in China. |
Countries
China
Contacts
Primary ContactXin Du, Doctor
Backup ContactYu Kong, Doctor
Outcome results
None listed