BMI and Lymph Node Count in Colorectal Cancer

Prediction of Survival in Colorectal Cancer Patients on the Basis of Body Mass Index and Lymph Node Yield - a Retrospective Single Center Cohort Analysis Over a Quarter of a Century

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06334926

Enrollment

1192

Registered

2024-03-28

Start date

2017-12-01

Completion date

2020-03-31

Last updated

2024-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The Aim of This Study is to Determine the Influence of BMI and Lymph Node Status on OS in CRC Patients in the Long Term

Keywords

colorectal cancer, survival, prognostic factors, body mass index, obesity paradox, lymph node count

Brief summary

Background and aim: Colorectal Cancer (CRC) is one of the most frequent cancer entities in the western world. It is known that obesity is one of the major risk factors for CRC. In contrast, mild obesity seems to have a positive effect on postoperative outcome, which is known as the obesity paradox. Also, the number of resected lymph nodes (LN) during surgery is very important for correct staging. The aim of the present project is to evaluate the impact of BMI and LN-yield on long term overall survival (OS) of CRC patients treated with curative intent. Methods: Patients treated for CRC between 1998 and 2011 at the Klinik Favoriten in Vienna, Austria were analyzed in this retrospective single-center cohort analysis concerning OS.

Interventions

OTHERno intervention, retrospective data analysis

not applicable, retrospective data analysis

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to 100 Years

Healthy volunteers

Inclusion criteria

* colorectal carcinoma * treated at the Klinik Favoriten between 1998 and 2011 * elective or acute surgical setting * curative intent * older than 18 years

Exclusion criteria

* other carcinoma (anal, metastases, ...) * treated before 1998 or after 2011 * palliative intent * younger than 18 years

Design outcomes

Primary

Measure	Time frame	Description
overall survival	median follow up of 11.3 years	The aim of the present project is to evaluate the impact of BMI and LN-yield on long term overall survival (OS) of CRC patients treated with curative intent.

Countries

Austria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026