Obstructive Sleep Apnea
Conditions
Keywords
Collapsibility of upper airways, Muscle responsiveness
Brief summary
In the framework of pathophysiological trait in obstructive sleep apnea (OSA) patients, a simplified method is proposed to measure upper airway (UA) collapsibility and muscle responsiveness during wakefulness.
Interventions
DIAGNOSTIC_TESTTests of upper airway collapsibility and muscle responsiveness.
Upper airway collapsibility, upper airway muscle responsiveness and loop gain will be assessed during single study visit. Polysomnography
Sponsors
Istituto Auxologico Italiano
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Obstructive Sleep Apnea (OSA) * At home-polygraphy with at least one EEG channel (PSG) reporting moderate-to severe obstructive sleep apnea (apnea-hypopnea index \>14).
Exclusion criteria
* OSA treatment ongoing during two weeks before PSG * Unstable cardio-respiratory disease in the 3 months before enrollment * Subjects in O2 treatment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Upper airway collapsibility | During the diagnostic test | Evaluation during wakefulness |
| Upper airway muscle responsiveness | During the diagnostic test | Evaluation during wakefulness |
Countries
Italy
Contacts
Primary ContactElisa Perger, MD
Outcome results
None listed