Healthy Adults
Conditions
Keywords
cross education, functional connectivity
Brief summary
We will explored the effect of cross education training on different cortex functional connectivity, cortex and muscle functional connectivity, and maximal voluntary contraction. Healthy participants receive cross education training of the elbow flexor (12 rep./set, 3sets, 60%MVC, 180°/s, eccentric).Maximal voluntary contraction, electroencephalogram and electromyogram will record during cross education tasks to determine the effects of cross education training on cortical network and muscle functional connectivity
Detailed description
Cross education (CE) training was observed in 1894, when unilateral strength training of single limb was found to increase in strength of untrained muscle group. CE has potential clinical relevance in rehabilitation for patient who have acute injuries of the limb, post-surgical limb immobilization and certain neurological disorders with unilateral muscle weakness. Although CE has several potential clinical application, the precise physiological mechanisms underlying CE remains unknown. Previous studies reported that CE may involve bilateral cortical activity in both contralateral primary motor cortex (cM1), and ipsilateral primary motor cortex (iM1).In addition, neuroimaging studies have demonstrated that bilateral supplementary motor area, but CE immediate change of functional connectivity in cortical network remains unknown. The purposes of this study are to investigate the immediate effect of CE training of biceps brachii (1) Immediate change of functional connectivity in cortical network; (2) Immediate change of functional connectivity in cortex and target muscle; (3) Explore immediate change of corticomuscular functional connectivity on maximal voluntary contraction. We hypothesize that (1) Bilateral cortical motor network that exhibit changes in functional connectivity during cross education; (2) Cross education would immediately enhance functional connectivity between cortex and target muscle; (3) Cross education would immediately change corticomuscular functional connectivity on maximal isometric voluntary contraction.
Interventions
OTHERCross education
Cross education training of the biceps brachii (12 rep./set, 3sets, 60%MVIC,180°/s, eccentric contraction)
Sponsors
National Yang Ming Chiao Tung University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Parallel Assignment
Eligibility
Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
1. Healthy adults who are 20-40 years old
Exclusion criteria
1. Upper extremity (UE) pain or discomfort 2. Medical condition that substantially influenced their UE strength 3. Experience of UE surgery 4. Paresthesia in UE 5. Open wound on UE
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Corticocortical coherence | Measured immediately after cross education training | Level of electroencephalography and electromyography synchronization in frequency domain when participants maintain 20% maximal voluntary contraction |
| Corticomuscular coherence | Measured immediately after cross education training | Level of electroencephalography and electromyography synchronization in frequency domain when participants maintain 20% maximal voluntary contraction |
| Maximal voluntary contraction | Measured immediately after cross education training | The ability to generate maximal voluntary elbow flexor force |
Countries
Taiwan
Outcome results
None listed