Contact Dermatitis
Conditions
Brief summary
Testing the effectiveness and safety of cosmetics with niacinamide in irritant contact dermatitis: A Randomised, Controlled Trial will be conducted at USSM. Healthy volunteers will be included (at least 25) and test sites are forearms. Sodium lauryl sulphate will be used to induce contact dermatitis and participants will be measured for 7 days
Detailed description
The efficacy of niacinamide cosmetic product on contact dermatitis will be evaluated using Courage Khazaka device and probes for hydration, redness and transepidermal water loss
Interventions
OTHERniacinamide cosmetic product
immortella skincare product
OTHERplacebo
nothing
Sponsors
University of Split, School of Medicine
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* young, healthy volunteers who gave written informed consent
Exclusion criteria
* skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| tewameter | day 1- day 7 | measurement of transepidermal water loss on skin, objective and non invasive |
Countries
Croatia
Contacts
Primary ContactJOSIPA BUKIĆ
Outcome results
None listed