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Effects of Different Concentric and Eccentric Muscle Fatigue Protocols on the Knee Joint Position Sense

Effects of Different Concentric and Eccentric Muscle Fatigue Protocols on the Knee Joint Position Sense: a Randomized Controlled Crossover Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06331221
Enrollment
22
Registered
2024-03-26
Start date
2023-11-02
Completion date
2024-05-15
Last updated
2024-07-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Muscle Fatigue, Knee, Joint Position Sense, Proprioception

Brief summary

The aim of this study was to investigate the effects of different concentric and eccentric muscle fatigue protocols on the knee joint position sense of healthy individuals.

Detailed description

A randomized controlled crossover trial will be conducted at a biomechanics laboratory with healthy males. All participants will perform with a washout period of 1 week: a control condition (5-minute rest) and 4 local muscle fatigue protocols (concentric of quadriceps; concentric of hamstrings; eccentric of quadriceps; eccentric of hamstrings) in an isokinetic dynamometer at 30º/s. Three maximum voluntary isometric contractions (MVIC) of quadriceps and hamstrings will also be assessed in the beginning of all conditions. Knee joint position sense will be assessed before and immediately after the fatigue protocols/control condition, through active concentric and eccentric positionings/repositionings, in sitting and prone positions, to a target range of 45º of knee flexion in an isokinetic dynamometer. Surface electromyography electrodes will also be placed on the vastus lateralis and biceps femoris during all procedures.

Interventions

Four experimental conditions consisting of different local muscle fatigue protocols performed in the isokinetic dynamometer in random order, with at least one week of interval between them.

Sponsors

Universidade do Porto
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* males aged between 18 and 30 years; * without current or previous knee pathology or surgery; * with a low or moderate physical activity level, according to the International Physical Activity Questionnaire; * normal Body Mass Index (under 24.9 kg/m2), according to the World Health Organization.

Exclusion criteria

* those with cardiorespiratory, neurological or vestibular pathologies; * with positive knee integrity tests (anterior drawer, Lachman's test, posterior drawer; valgus and varus stress testes); and * those taking any medication that can affect motor control (sedatives, anxiolytics, antibiotics, analgesics, NSAIDs or myorelaxants).

Design outcomes

Primary

MeasureTime frameDescription
Absolute angular errorChange from Baseline (Before) to Immediately after interventions or control (After)The absolute value of the difference between the target range and the achieved range
Relative angular errorChange from Baseline (Before) to Immediately after interventions or control (After)The arithmetic difference between the target range and the range achieved
Variable angular errorChange from Baseline (Before) to Immediately after interventions or control (After)The standard deviation of the 3 repositionings

Countries

Portugal

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026