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Physiotherapy and Reaction Time in Hemophilia

The Effectiveness of Low Frequency Comprehensive Physiotherapy Combined With Home Exercise on Joint Health, Frequency of Hemartrosis, Dynamic Balance and Reaction Time in Hemophilic Arthropthy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06331091
Enrollment
21
Registered
2024-03-26
Start date
2022-12-10
Completion date
2024-01-19
Last updated
2024-04-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemophilia Arthropathy

Keywords

hemophilia, physiotherapy, exercise, reaction time, joint health, arthropathy

Brief summary

This randomised controlled study was conducted to investigate the comprehensive physiotherapy combined with home exercises on individuals with hemophilic arthropathy in the lower extremity. There are two groups in the study: home exercises and comprehensive physiotherapy combined with home exercises. Is physiotherapy combined with home exercises superior to home exercises on joint health, bleeding frequency, reaction time, dynamic balance, muscle strength? The aim of this study is to increase the compliance of hemophilic individuals to physiotherapy and adapt home exercises to their lives with weekly sessions.

Detailed description

Introduction: The positive effects of physiotherapy and exercise on joint health, frequency of hemartrosis (FoH) in patient with hemophilic arhropathy (PwHA) are well explained in the literature. However, adaptation problems to physiotherapy sessions (usually 3 times a week) may cause PwHA to ignore the need for therapy. It may be more beneficial for PwHA to adapt physiotherapy and exercise into daily live. Aim: To investigate the effect of a once-a-week physiotherapy combined with home exercises on joint health, FoH, muscle strength, pain, reaction time and dynamic balance. Methods: 20 patients have hemophilic arthropathy in knee and/or ankle were randomly divided into 2 groups, named home exercise (HE) and comprehensive physiotherapy combined with home exercise (CPcwHE). In the clinical assessment, HJHS, manuel muscle tester, Fitlight® system for reaction time, functional reach test for dynamic balance were used and questioned the number of bleedings in the last 6 weeks for FoH. The CP group received comprehensive physiotherapy (manual therapy, neuromuscular electrical stimulation and exercises) 1 day a week, and did the exercises at home the other 2 days a week. The HE group performed the exercises given to CP at home 3 times a week. Evaluations were repeated at the end of 6 weeks.

Interventions

OTHERHome exercise

Home exercise are done at home without the supervision of a specialist.

OTHERManual therapy

Manual therapy is special techniques for soft tissues and joints applied by a physiotherapist.

DEVICENeuromuscular electrical stimulation

Home exercise are done at home without the supervision of a specialist. Manual therapy is special techniques for soft tissues and joints applied by a physiotherapist. Neuromuscular electrical stimulation is the application of electrical current to the muscle through special electrodes in order to increase muscle strength. Supervised exercise is done under the supervision of a physiotherapist.

OTHERSupervised exercise

Supervised exercise is done under the supervision of a physiotherapist.

Sponsors

Yuzuncu Yil University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

Randomised controlled study

Eligibility

Sex/Gender
MALE
Age
10 Years to 32 Years
Healthy volunteers
No

Inclusion criteria

-Clinical diagnosis of hemophilia -Clinical diagnosis of hemophilic arthropathy in ankle and/or

Exclusion criteria

* Clinical diagnosis of any neurological disease

Design outcomes

Primary

MeasureTime frameDescription
Hemophilia Joint Health Score6 weeksJoint health (Max values= 84, min values=0. As the value increases, joint health worsens.)
Reaction time6 weekDynamic balance

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026