Diabetes Mellitus, Type 2
Conditions
Brief summary
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by hyperglycemia, weight loss, and cardio-metabolic complications. T2DM develops due to the progression of insulin resistance (IR), impairment of insulin insensitivity, and failure of the pancreatic β-cells to release sufficient amount of insulin in response to glucose burden
Interventions
Sitagliptin is used along with diet and exercise and sometimes with other medications to lower blood sugar levels in adults with type 2 diabetes
DRUGDoxycyclin
Doxycycline belongs to the class of medicines known as tetracycline antibiotics. It works by killing bacteria or preventing their growth.
Sponsors
Mostafa Bahaa
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Masking description
open label
Intervention model description
open label
Eligibility
Sex/Gender
ALL
Age
40 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Male or female sex more than 40 years old Newly diagnosed type II diabetes. HbA1c more than 6.5
Exclusion criteria
* Patient with chronic kidney disease, hepatic disorders, mental and psychiatric disorders, pregnancy, and lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in glycemic profile | 3 months | measurement of fasting blood glucose (FBG) |
Countries
Egypt
Outcome results
None listed