Child Allergy, Neurodevelopmental Disorders
Conditions
Brief summary
In this study, a birth cohort was established to demonstrate the causal relationship between allergies and neurodevelopment disorders in infants and young children, and to find out the influencing factors of neurodevelopment disorders in early life.
Detailed description
In this study, a birth cohort was established, and infants were divided into two groups according to inclusion and exclusion criteria ( see study design ). One group was allergic group, and the other group was control group. The two groups will be followed up for up to 6 years, and specimens ( blood, urine, feces ) and test data ( height, weight, GESELL, etc. ) will be retained during the follow-up period. The outcome indicators were ASD, ADHD or LD, and DSM-5 was used as the diagnostic criteria.
Interventions
None listed
Sponsors
Qilu Hospital of Shandong University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Minutes to 42 Days
Inclusion criteria
* ①Allergic questionnaire results were positive. * The living area is Jinan City and its surrounding areas in Shandong Province, which is convenient for follow-up.
Exclusion criteria
* There is a clear diagnosis of brain developmental disorders * Psychological diseases * History of craniocerebral trauma or brain organic disease ④Major physical diseases ⑤Visual and auditory disorders ⑥ Epilepsy ⑦Intellectual disabilities
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ASD | from 2023-11-15 to 2026-11-15 | with diagnostic criteria of DSM-V ASD, and ADOS, CARS auxiliary diagnosis. |
| ADHD | from 2023-11-15 to 2029-11-15 | with diagnostic criteria of DSM-V ADHD, and SNAP-Ⅳ, CONNER auxiliary diagnosis. |
Countries
China
Contacts
Primary Contactcao aihua, post-doctoral
Backup Contactzhu mengna, postgraduate
Outcome results
None listed