Skip to content

Artificial Intelligence Based Program to Classify Oral Cavity Findings Based on Clinical Image Analysis

The Application of an Artificial Intelligence Based Program to Classify Oral Cavity Findings Based on Clinical Image Analysis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06325514
Enrollment
241
Registered
2024-03-22
Start date
2024-04-01
Completion date
2024-12-01
Last updated
2025-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Erythroplakia, Fordyce Granule, Leukoedemas, Oral, Leukoplakia, Lichenoid Reaction, Oral Cancer, Oral Lichen Planus

Brief summary

This study aims to develop an AI program that can classify oral findings into Normal/variation of normal or an oral disease by clinical photos analysis, aiding in lowering the percentages of false positive and false negative diagnosis of oral diseases.

Detailed description

Early diagnosis of oral lesions, particularly oral cancer, is crucial for enhancing prognosis, facilitating early intervention and care with the intention of lowering disease-related mortality. Since conventional oral examination (COE) is the most used method in identifying oral lesions, the average dental practitioner's experience is a decisive factor in early diagnosis. Visual examination lacks specificity and sensitivity since its highly subjective. Unfortunately, Studies show that the majority of dentists lack expertise in early detection of the disease, resulting in false negative diagnosis of oral lesions. General practitioners are found to either delay the referral of a suspected oral lesion to an Oral Medicine specialist, or referring numerous false positive cases, unnecessarily pushing the patients into a state of anxiousness and cancer phobia. False positive referrals overburden the specialists, which will eventually cause delayed diagnosis of true positive cases due to the oversaturation with false positive ones. diagnostic research scope shifts towards noninvasive, easy chair side methods with higher accuracy for early detection of oral lesions. Recent approaches towards using machine based programs indicate that this machine-learning method may be useful in the detection and diagnosis of oral cancer.

Interventions

DIAGNOSTIC_TESTArtificial intelligence based program

the AI based program is based on image analysis

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Patients above 18 years old * Candidates with normal oral cavity findings * Candidates with variations of oral cavity findings * Candidates with different oral lesions

Exclusion criteria

• Patients less than 18 years old

Design outcomes

Primary

MeasureTime frameDescription
risk stratification3 months to develop the programpatient is either normal with no risk or need for referral, low risk of malignant transformation disease, high risk of malignant transformation disease.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026