Colorectal Cancer
Conditions
Keywords
colorectal, cancer, recurrence, prognosis
Brief summary
over the past decade colon cancer has emerged as the second most deadly and the third most common type of cancer in the world with increasing incidence in Egypt due to life style and diet change. some research showed relation between colon cancer recurrence and advanced tumor staging. To investigators knowledge, this is the first time to be done in Zagazig University. Data was collected from records in a retrospective cohort study
Interventions
PROCEDUREresection of colorectal cancer
resection of bowel segment and re-anastmosis or stoma formation
Sponsors
Zagazig University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Adult patients with newly diagnosed colorectal cancer * Age \> 18 years old * recurrent cases of colorectal cancer
Exclusion criteria
* Pediartric patient less than 18 yr * In operable or metastatic cancer colon * No other malignancies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| age | through study completion, an average of 5 years | age of patients was obtained from medical records |
| sex | through study completion, an average of 5 years | sex of patients was obtained from medical records |
| medical disease | through study completion, an average of 5 years | co-existing medical disease was obtained from medical records |
| previous surgery | through study completion, an average of 5 years | previous surgical history was obtained from medical records |
| CEA | through study completion, an average of 5 years | value of carcino-embryonic antigen was recorded |
| tumor grade | through study completion, an average of 5 years | tumor grade after resection from pathology report recorded |
| tumor site | through study completion, an average of 5 years | tumor site recorded from operative findings |
| tumor size | through study completion, an average of 5 years | tumor size was measured by length x width in cm from records |
| surgical margins of resected tumor | through study completion, an average of 5 years | safety margins were assessed from pathological examination under microscopy and recorded in pathology reports, it can be free surgical margins ( no tumor cells) or positive surgical margins( presence of tumor cells) |
| neoadjuvant therapy | through study completion, an average of 5 years | history of neoadjuvant therapy before surgery from records obtained |
| adjuvant therapy | through study completion, an average of 5 years | history of adjuvant therapy post operative obtained from records |
| diet | through study completion, an average of 5 years | diet and dietary life style from history |
| occupation | through study completion, an average of 5 years | occupation of the patient at time of surgery and if it was changed |
| family history | through study completion, an average of 5 years | history taking of family history of cancer disease |
| type of surgery(laparoscopic or open) | through study completion, an average of 5 years | type of operation was laparoscopic or open surgery obtained from records |
| soiling by during surgery | through study completion, an average of 5 years | by history from records if there was soiling of the field by tumor cells |
| hand sewen or stappled anastmosis | through study completion, an average of 5 years | if there was bowel re-anastmosis after surgery, it was done using a stappler or hand sewing sutures. this was obtained from operative data in patient records |
| post operative complications | through study completion, an average of 5 years | from records; if there were post operative complication like fecal fistula |
| site of recurrence | through study completion, an average of 5 years | site of tumor recurrence was detected |
| type of resected tumor | through study completion, an average of 5 years | type of tumor was recorded from pathology reports |
Countries
Egypt
Outcome results
None listed