Validating the Use of Frailty Measurements to Predict Care & Quality of Life

Validating the Use of Frailty Measurements to Predict Care Expectations and Deteriorations in Quality of Life Among People With COPD: A Prospective Cohort Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06325241

Enrollment

123

Registered

2024-03-22

Start date

2022-12-12

Completion date

2025-03-31

Last updated

2024-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

Frailty, Care expectations

Brief summary

The aim of this research program is to validate frailty measurements as a risk stratification tool to predict deteriorations in patient-reported outcomes, to gain a better understanding of patient preferences for care within varying degrees of frailty, and to assess differences in frailty measurement between patients and their clinicians. This work will provide a foundation in the development of customized interventions for people with COPD and varying degrees of frailty, with the goal of improving quality of life and optimizing health system service delivery for patients and their care givers.

Interventions

OTHERNo intervention

There is no intervention. This is an observational study.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Outpatients of The Ottawa Hospital Respirology clinic * Chronic Obstructive Pulmonary Disease diagnosis confirmed by pulmonary function testing. * English or French speaking

Exclusion criteria

* patients with a known diagnosis of severe cognitive impairment

Design outcomes

Primary

Measure	Time frame	Description
Respiratory Health Related Quality of Life	12 months	measured by the validated short version of St. Georges Respiratory Questionnaire (not a scale).

Secondary

Measure	Time frame	Description
Burden of symptoms - COPD Assessment	12 months	measured with the COPD Assessment Test where 0 means no symptoms and 5 means severe symptoms of COPD.
Burden of symptoms - Dyspnea	12 months	measured with the modified Medical Research Council scales. Measured on a scale of 0-4 where 0 means not breathless and 4 is too breathless.
Psycho-social well being - Anxiety	12 months	measured with the validated Generalized Anxiety Disorder-7. GAD-7 results vary between 0 and 21, the higher the score, the more anxiety.
Psycho-social well being - Depression	12 months	measured with the Patient Health Questionnaire-8 scales. PHQ8 results vary between 0 and 24, where the higher the number, more severe is the persons' level of depression.

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026