Pneumonia, Probiotics
Conditions
Keywords
pneumonia treatment, probiotics
Brief summary
Probiotics as adjuvant therapy along with standard care can decrease hospital stay and improve symptoms (fever, tachypnea,cough) in pediatric patients admitted with severe pneumonia.
Detailed description
After getting written informed consent from parents/attendants, all patients aged 6 month-2yrs admitted with severe pneumonia in pediatric wards of children hospital, during the study time of 6 month will be recruited.After applying exclusion criteria remaining participants will be included in the study. The study population will be randomized in to two groups, Group A will be given probiotic sachet and group B will be given simple milk as placebo.The patients and their parents/attendants will be kept blind to the fact that they are receiving either probiotic or placebo The probiotic and placebo mixture will be given daily for three days.The patients in both the groups will be followed for the duration of illness until they are either discharged or show any adverse outcomes of pneumonia.Total days of admission will be recoded for patients discharged from hospital.Parents will be asked questions regarding improvement in symptoms like fever on discharge. Duration for Improvement in tachypnea andcough will be noted for all patients. Outcomes will be duration of hospital admission, improvement in fever, tachypnea and cough.All the data collected will be entered and analyzed using SPSS latest version and analysed.
Interventions
probiotic containing Lactobacillus rhamnosus GG will be given daily for 3 days
milk as placebo
Sponsors
Study design
Masking description
The patients and their parents/attendants will be kept blind to the fact that they are receiving either probiotic or placebo
Intervention model description
randomized control trial
Eligibility
Inclusion criteria
Patient aged 2month-24months. Both male and female children
Exclusion criteria
Patients with severe acute malnutrition Patients with very severe pneumonia Patients with Other concurrent infections Patients having any chronic debilitating condition Children who took probiotics in past 6 months Patient requiring mechanical ventilation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of days in hospital | 6 month | hospital stay in patients admitted with severe pneumonia. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of days with cough, fever | 6 month | Improving symptoms in patients admitted with severe pneumonia. |
Countries
Pakistan