Surgical Resection Outcomes in Patients With Brain Metastasis

Prognostic Factors Impacting Surgical Resection Outcomes in Patients With Brain

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06318065

Enrollment

100

Registered

2024-03-19

Start date

2010-01-01

Completion date

2024-09-01

Last updated

2024-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Metastases

Brief summary

While many studies have investigated the prognostic factors for patients undergoing surgical resection for primary brain tumors, decision-making for patients with brain metastasis (BM) is more complex because of their higher burden of comorbidities compared to those with primary brain tumors. In addition, although various prognostic indicators have been identified to predict prognosis in several types of cancer, such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), prognostic nutritional index (PNI), and systemic immune-inflammation index (SII), limited studies have yet determined which group of patients would yield beater survival outcome after surgical resection for BM. This study aimed to investigate the impact of patient and perioperative characteristics and prognostic indicators on survival outcome of patients undergoing surgical resection of BM.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. patients with Clinical diagnosis of brain metastasis 2. patients who underwent craniotomy surgery for brain metastasis

Exclusion criteria

1. patients with insufficient data for associated factors 2. patients who underwent stereotactic biopsy for brain metastasis 3. patients who did not undergo craniotomy surgery for brain metastasis

Design outcomes

Primary

Measure	Time frame	Description
survival outcome of patients undergoing surgery for brain metastasis	From date of surgery until the date of death from any cause, whichever came first, assessed up to 100 months	overall survival of patients
Functional outcome of patients undergoing surgery for brain metastasis	from date of surgery until 6 months after surgery ordate of death from any cause, whichever came first	change of preoperative and postoperative modified rankin scale

Countries

Taiwan

Contacts

Primary ContactJung-Shun Lee, M.D.

nslee1218@gmail.com886-6-2353535

Outcome results