Esophageal Cancer
Conditions
Brief summary
The main objective of the first part of the study is to determine the most optimal method for DIBH (active breathing control vs voluntary coached) and its reproducibility. Based on these findings, one of these methods will be selected for part 2 of this study.
Interventions
OTHERDIBH using ABC technique
Deep breath inspiration hold (DIBH) using Active Breathing Control (ABC) technique
OTHERDIBH using VC technique
Deep breath inspiration hold (DIBH) using Voluntary Coaching (VC) technique
Sponsors
University Medical Center Groningen
Study design
Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
The participating patients will undergo weekly (during radiotherapy treatment) 2 CTs in DIBH; one using ABC and one using voluntary coaching (VC).
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Histologically proven esophageal cancer of the mid or distal esophagus * Scheduled for external-beam photon radiotherapy with curative intention. * WHO 0-2. * Age \>= 18 years * Written informed consent.
Exclusion criteria
* Serious respiratory distress * Contra-indication for fiducial marker placement * Noncompliance with any of the inclusion criteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Feasibility DIBH | Week 1, 2, 3, 4, 5 during radiotherapy | Breath hold maintained for \>20 seconds |
| Reproducibility DIBH | Week 1, 2, 3, 4, 5 during radiotherapy | Diaphragm dome position within 1cm of the baseline CT Target coverage \>94% of the prescribed dose (at 98% of the ITV) |
Countries
Netherlands
Outcome results
None listed