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Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis

Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis During Organ-preserving Surgery

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06316154
Acronym
PAFCLE
Enrollment
100
Registered
2024-03-18
Start date
2023-10-22
Completion date
2026-12-25
Last updated
2025-12-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Echinococcosis, Hepatic

Brief summary

The objective of the study is to determine the presence of germinal elements of echinococcosis in the liver parenchyma next to and in the thickness of the fibrous capsule of hydatid cysts.

Interventions

PROCEDUREEchinococcectomy

Echinococcectomy with subsequent pathomorphological analysis of liver parenchyma next to and in the thickness of the fibrous capsule

Sponsors

Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Presence of primary or recurrent liver echinococcosis disease requiring surgical treatment * Cyst diametr \>5 cm; * Performing one of the surgical treatment of liver echinococcosis with intraoperative sampling of part of the fibrous capsule with or without adjacent liver tissue for research; * Signed informed consent of patients for inclusion in the study;

Exclusion criteria

* Liver echinococcosis with cysts less than 5 cm in diametr; * Presence of severe concomitant disorders

Design outcomes

Primary

MeasureTime frameDescription
Presence of viable germinal elements of echinococcosis1 dayIdentification of viable germinal elements of echinococcosis according to morphological analysis

Secondary

MeasureTime frameDescription
Recurrence of liver echinococcosis1 yearIdentification of frequency of liver echinococcosis in postoperative period

Countries

Uzbekistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026