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Assessing and Addressing Community Exposures to Environmental Contaminants

Building Food Sovereignty, Sustainability and Better Health in Environmentally-impacted Native Americans

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06315140
Enrollment
400
Registered
2024-03-18
Start date
2023-02-16
Completion date
2027-04-01
Last updated
2026-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Environmental Exposure

Keywords

Ramapough Nation, metals, food, nutrition

Brief summary

The purpose of this study is to build on our equitable, eight-year Tribal-academic partnership with the Ramapough Nation of northern NJ to advance tradition-centered farming practices and management strategies supporting sustainable food systems to relieve local food insecurity and nutritional deficiency, prevent disease and promote health. Furthermore, assessing the extent of environmental contamination, individual toxicant burdens and micronutrient levels and health disorders in Ramapough Tribal members of both sexes as outlined in the following: * Collect in-person/online survey information on demographics, health and food intake, nutrition, food security, and psychosocial stressors, and perform core anthropometric measurements (i.e., height, weight, body mass index, body circumference and blood pressure) at enrollment on Tribal members to inform health promotion strategies and community actions. * Determine individual-level contaminant burdens and micronutrient concentrations (e.g., iron, calcium, folate, vitamins) in urine and blood from surveyed (sub-aim 1a) Ramapough Turtle Clan volunteers. * Test soil, plants and surface water where Turtle Clan residents live, recreate and attend church in Ringwood, NJ using a community-based, citizen scientist approach.

Interventions

OTHERNutrition

The intervention will build on the 11-year Tribal-academic partnership with the Ramapough Nation of northern NJ to advance tradition-centered farming practices and management strategies supporting sustainable food systems to relieve local food insecurity. Working with the Ramapough-leased Munsee Three Sisters Medicinal farm (growing produce/crops on clean soil) will provide the tribe with nutrition-rich foods and recipes for nutritious cooking. The interventions aims to return healthy soil on the farm allowing for healthy plant production.

Sponsors

NYU Langone Health
Lead SponsorOTHER
National Institute of Environmental Health Sciences (NIEHS)
CollaboratorNIH

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

* Male or female between the age of 18 - 80 years old at the time of enrollment * Living on the streets of Halifax Road, Orange Turnpike, Ramapo Ave, 1st-7th Streets, Mountain Avenue and Fox Hollow Road in Hillburn, NY; Peter's Mine Road, Canon Mine Road, Pipeline Road, Milligan Drive, Cable House Road and Van Dunk Lane in Ringwood, NJ; Stag Hill Road, and Ramapo Brae Lane in Mahwah, NJ * Willing and able to provide consent

Exclusion criteria

* Pregnant women and individuals under 18 or over 80 years old * Do not live in the identified streets above and/or have lived there for less than 2 years will be excluded from the study

Design outcomes

Primary

MeasureTime frameDescription
Proportion of individuals with heavy metal contaminants in home water samplesthrough study completion, an average 2 yearsOutcome measures will be collected using home water samples.
Proportion of individuals with heavy metal and metalloid contaminations in blood biospecimensthrough study completion, an average 2 yearsOutcomes measures will be evaluated using blood samples from the Ramapough Lunaape Tribe.
Proportion of individuals with heavy metal and metalloid contaminations in urine biospecimensthrough study completion, an average 2 yearsOutcomes measures will be evaluated using urine samples from the Ramapough Lunaape Tribe.
Proportion of individuals with insufficient blood serum micronutrient levelsthrough study completion, an average 2 yearsOutcome measures will be evaluated using blood serum from the Ramapough Lunaape tribe.
Proportion of individuals with health disordersthrough study completion, an average 2 yearsHealth status will be assessed using anthropometric measures including blood pressure, body weight, waist circumference, height and Body Mass Index (BMI).

Countries

United States

Contacts

CONTACTJudith T. Zelikoff, PhD
Judith.zelikoff@nyulangone.org646-754-9451
CONTACTErica Pratt
erica.pratt@nyulangone.org646-754-9447
PRINCIPAL_INVESTIGATORJudith Zelikoff, PhD

NYU Langone Health

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026