Liver Transplant Disorder
Conditions
Brief summary
Liver transplant surgery is one of the treatments provided to patients suffering from end-stage liver disease, and has a successful treatment prognosis. However, it is clear that patient management before, during, and after surgery is a difficult task for medical staff due to the complex clinical and pathological problems of end-stage liver disease. Moreover, the complex surgical technique of the liver transplant surgery itself and the severe hemodynamic fluctuations and multi-organ dysfunction that patients experience during the surgery have been shown to have a tremendous impact on the patient's prognosis after surgery. A study on which clinical, laboratory, and hemodynamic factors experienced by patients during the perioperative period, including before, during, and after surgery, affect the survival rate of patients and transplanted organs. will definitely be helpful in the treatment of patients suffering from end-stage liver disease.
Interventions
After induction of anesthesia, the paired RIPC group took the RIPC intervention on the upper arm in the lateral position. The RIPC intervention was applied using a manual cuff inflator, which consisted of three cycles of 5-min inflation of the blood pressure cuff (to 250 mmHg, or to 50 mmHg higher than the preoperative SBP), followed by 5-min deflation of the cuff. In the no-RIPC group, a blood pressure cuff was also applied on the upper arm but was not inflated.
Sponsors
Study design
Eligibility
Inclusion criteria
* adults * elective surgery * American Society of Anesthesiologists (ASA) physical status classification system I, II, III
Exclusion criteria
* American Society of Anesthesiologists (ASA) physical status classification system IV, V
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of postreperfusion syndrome | during surgery | mean blood pressure decreases by 30% based on the value on preoperative day |