Necrotic Pulp
Conditions
Keywords
Asymptomatic Necrotic Mandibular Premolar
Brief summary
Clinically compare the post-operative pain , incidences post-operative swelling , post-operative number of analgesic tablets taken by patient and amount of bacterial load reduction after using 50% Commiphora Myrrh Chemomechanical preparation , versus 2.5% NaOCl,in asymptomatic necrotic mandibular premolar treated in single visit.
Detailed description
The patients will be randomly divided into 2 groups. Intervention group (50% Commiphora Myrrh solution root canal irrigant) and control group (2.5% sodium hypochlorite root canal irrigant) Post-operative pain will be measured at 6,12,24,48 hours post-operatively The pain will be recorded using numerical rating scale Post-operative swelling will be measured at 6,12,24,48 hours post-operatively The swelling will be receded using visual swelling rating scale Number of analgesic tablets taken by the patient post-operatively. Up to 48 hours Amount of bacteria load reduction The intracanal bacterial load reduction will be determined using agar culture technique by counting the colony forming units per milliliter (CFI /ml) before and after root canal preparation.
Interventions
OTHERRoot canal irrigant Commiphora Myrrh 50%
Root canal irrigant
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
1. Systemically healthy patient (ASA I, II). 2. Age between 20 and 40 years. 3. Male or female. 4. Patient who is able to sign and comprehend the pain scale (committed patient). 5. Mandibular single rooted premolars having the following criteria: * With single root canal. * Diagnosed clinically with pulp necrosis. * Absence of spontaneous pulpal pain. * Positive pain on percussion denoting apical periodontitis. * Slight widening of periodontal space or peri-apical radiolucency smaller than 3 mm (0-2mm)
Exclusion criteria
1. Medically compromised patients (ASA III or IV). 2. Teeth with: 3. Patients who could not interpret the NRS. * Immature roots. * Vital pulp tissues. * Association with swelling. * Acute peri-apical abscess or acute exacerbation of a chronic abscess. * Mobility Grade II or III. * Previously accessed or endodontically treated. * Deep periodontal pockets more than 4 mm. * Vertical root fractures, coronal perforation, calcification, and external or internal root resorptions. 4. Patients with diabetes, immune-compromising, and immunosuppression disease and pregnant women will be also excluded. 5. History of intolerance to NSAIDs.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Post-operative pain | Post-operative pain measured at 6,12,24,48 hours after single visit Treatment | Categorical None 0 Mild 1-3 Moderate 4-6 Sever 7-10 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| incidence of Post-operative swelling | Up to 48 hours post- | Categorical Of visual swelling scale of post- operative |
Other
| Measure | Time frame | Description |
|---|---|---|
| Amount of intracanal Bacterial CFUs/ml | Pre-intervention, pre-instrumentation after access cavity. Post-instrumentation up to 10min | Intra canal bacterial load reduction will be determined using agar culture technique by counting the colony forming units per milliliter (CFUs/ml) before and after root canal preparation |
| Number of analgesic Counting Tablets taken by the patient after endodontic treatment | Up to 48hours post-operative | Counting the tablet after the treatment |
Contacts
Primary ContactRahaf A Manzalawi, BDS
Outcome results
None listed