Periodontitis
Conditions
Keywords
Periodontitis, Hyaluronic Acid, Oral Hygiene
Brief summary
This study aimed to compare the effects of using an interdental brush dipped in 0.2% HA gel with those of using a regular interdental brush on clinical periodontal parameters following SRP among patients with periodontitis.
Detailed description
The additional use of agents with antibacterial and anti-inflammatory activities such as hyaluronic acid (HA) in treating periodontal disease has recently become popular. This study aimed to evaluate the effects of using an interdental brush dipped in 0.2% HA gel on clinical periodontal parameters.This randomized controlled trial was conducted among 33 female patients and 27 male patients with stage II/III grade A/B periodontitis. After the initial periodontal treatment, patients were randomly divided into two groups; those in the test group were asked to use an interdental brush dipped in 0.2% HA gel twice a day after brushing, while those in the control group were asked to use a regular interdental brush. Clinical periodontal parameters including the pocket depth, clinical attachment loss, gingival index, plaque index, and papillary bleeding index (PBI) were assessed at baseline and in the 1st and 3rd months after treatment.
Interventions
DEVICEInterdental brush+HA
interdental brushes (TePe Munhygienprodukter AB, Malmö; TePe 0.4 mm and TePe 0.6 mm) +20 mL of 0.2% HA gel (Gengigel; Ricerfarma, Milan, Italy)
DEVICEInterdental brush
interdental brushes (TePe Munhygienprodukter AB, Malmö; TePe 0.4 mm and TePe 0.6 mm)
Sponsors
Özlem SARAÇ ATAGÜN
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Masking description
The investigator carrying out the measurements was not aware of which patients were assigned to the test group.
Intervention model description
single-center, single-blinded, randomized controlled trial
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. ≥18-55 years of age 2. Being systemically healthy 3. Having periodontitis (Stage 3) 4. Not to have used any medication in the last three months 5. Not smoking 6. Right-handed 7. At least 20 natural teeth
Exclusion criteria
1. Patients with interdental caries 2. Patients with orthodontic appliances 3. Patients with removable (partial) prostheses 4. Patients with oral and/or peri-oral pain 5. Patients with significant oral lesions 6. Patients with antibiotic use in the last 3 months, pregnancy and breastfeeding 7. Patients who have undergone periodontal treatment within the last 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Gingival index (GI) | Baseline-4 weeks-12 weeks | Improvement in GI; lower scores mean a better outcome; Minimum score:0 Max.score: 3 |
| Plaque index (PI) | Baseline-4 weeks-12 weeks | Improvement in PI; lower scores mean a better outcome; Minimum score:0 Max.score: 5 |
| Papillary bleeding index (PBI) | Baseline-4 weeks-12 weeks | Improvement in PBI; lower scores mean a better outcome; Minimum score:0 Max.score: 3 |
| Pocket depth (PD) | Baseline-4 weeks-12 weeks | Improvement in PD; lower scores mean a better outcome |
| Clinical attachment loss (CAL) | Baseline-4 weeks-12 weeks | Improvement in CAL; lower scores mean a better outcome |
Countries
Turkey (Türkiye)
Outcome results
None listed