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Calcified Cerebral Embolism: a Descriptive Study in a Large Single Center Cohort

Calcified Cerebral Embolism: a Descriptive Study in a Large Single Center Cohort

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06309069
Acronym
CCE Cohorte
Enrollment
79
Registered
2024-03-13
Start date
2024-04-16
Completion date
2024-11-30
Last updated
2026-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Calcified Cerebral Embolism

Keywords

calcified cerebral embolism, cerebral infarction, radiological characteristics

Brief summary

Calcified cerebral embolism (CCE) is a relatively rare but underdiagnosed cause of infarction. CCE diagnosis is made by CT. Radiological characteristics of CCE have been reported in small case series. The aim of this study was to describe clinical and radiological characteristics of CCE in a large number of patients, and to compare patients with different radiological CCE characteristics.

Interventions

None, purely observational study

Sponsors

Centre Hospitalier Universitaire de Nīmes
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Patients with CEE treated with intravenous thrombolysis (IVT) between 2015 and 2020 managed at the CHU de Nîmes or Patients with TIA/stroke with ECC identified on CT between 12/2019 and 04/2023 managed at CHU de Nîmes

Exclusion criteria

* Patient's refusal to use his/her data

Design outcomes

Primary

MeasureTime frameDescription
Calcified aortic brachiocephalicbaselinelooking for calcified aortic brachiocephalic (presence or absence)
cardiovascular riskbaselineStudy of cardiovascular risk factors (presence or absence)
history of strokebaselinePresence of a history of stroke (y/n)
Populationbaselinedemographic characteristics age (years)
history of surgical/endovascular cardiovascular interventionbaselinesurgical/endovascular cardiovascular intervention (y/n)
NIHSSbaselineNIHSS score (Score between 1 and 4: minor stroke, Score between 5 and 15: moderate, stroke, Score between 15 and 20: severe stroke) Score \> 20: severe stroke
calcified aortic archbaselinelooking for calcified aortic arch (presence/absence)
calcified carotidbaselinelooking for calcified carotid (presence/absence)
atherosclerotic plaquesbaselinelooking for atherosclerotic plaques (presence/absence)
calcified aortic valvesbaselinelooking for calcified aortic valves (presence/absence)
calcified mitral valvesbaselinelooking for calcified mitral valves (presence/absence)
CCE diameterbaselineCCE diameter measurement (mm)
densitybaselineCCE density (uh)
involved cerebral arterybaselinedescription of involved cerebral artery

Countries

France

Contacts

STUDY_DIRECTORAnissa MEGZARI

Centre Hospitalier Universitaire de Nīmes

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026