Seminal Levels of PGK2 and ACRV1 as Predictors of Micro-TESE Results in NOA

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06307639

Enrollment

Registered

2024-03-13

Start date

2024-04-01

Completion date

2026-04-01

Last updated

2024-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male Infertility Due to Azoospermia

Brief summary

* Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE). * Correlate seminal levels of PGK2 and ACRV1 with sperm retrieval results and histopathology analysis of testicular biopsy samples.

Interventions

DIAGNOSTIC_TESTMeasurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE).

Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE).

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* Infertile males with normal volume, functional (non-obstructive) azoospermia. * Age: 18-45 years

Exclusion criteria

* Patients with proven obstructive azoospermia. * Cryptorchidism. * Testicular Agenesis and testicular atrophy. * Patient with exposure to gonadal toxins like chemotherapy, radiotherapy, and alkylating agents.

Design outcomes

Primary

Measure	Time frame
Know more about the functional role of PGK2 and ACRV1 in the process of spermatogenesis.	2 years
Detect if PGK2 and/or AVRV1 level can used as predictor for spermatogenesis in infertile men with non-obstructive azoospermia undergoing Testicular Sperm Extraction.	2 years

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026