Gingivitis
Conditions
Keywords
Hyaluronic Acid, Dental Floss, Gingivitis, Oral Hygiene
Brief summary
This study aimed to evaluate the effects of 0.2% HA-impregnated dental flosses on the clinical periodontal parameters of patients with gingivitis.
Detailed description
Gingivitis is a common inflammatory lesion caused by the build-up of oral biofilm and is an essential precursor to periodontitis. For its treatment, oral hygiene habits, such as dental flossing, must be improved, and adjunctive materials, such as hyaluronic acid, may be used to reduce plaque formation and gingival inflammation. This study aimed to assess the effects of 0.2% hyaluronic acid gel (Gengigel®)-impregnated dental flosses on the clinical periodontal markers of patients with gingivitis. This clinical study adopted a split-mouth, randomized controlled trial design. After clinical data were assessed at baseline, and supragingival scaling and planing was performed, bilateral gingivitis regions were randomly allocated to either a test group (hyaluronic acid gel-impregnated floss) or a control group (regular floss) using a computer-generated randomization table. Clinical parameters were recorded at 1, 2, and 4 weeks after treatment.
Interventions
DEVICEDental floss+Gengigel
0.2% Hyaluronic Acid Gel-Impregnated Dental Flosses
DEVICEDental Floss
Dental Flosses
Sponsors
Özlem SARAÇ ATAGÜN
Study design
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Investigator)
Masking description
The investigator who performed the measurements was blinded to which side of patients was the test group
Intervention model description
single-center, single-blinded, split-mouth, randomized clinical trial
Eligibility
Sex/Gender
ALL
Age
18 Years to 47 Years
Healthy volunteers
No
Inclusion criteria
1. ≥18-55 years of age 2. Being systemically healthy 3. Having gingivitis 4. Not to have used any medication in the last three months 5. Not smoking 6. Right-handed 7. At least 20 natural teeth
Exclusion criteria
1. Patients with interdental caries 2. Patients with orthodontic appliances 3. Patients with removable (partial) prostheses 4. Patients with oral and/or peri-oral pain 5. Patients with significant oral lesions 6. Patients with antibiotic use in the last 3 months, pregnancy and breastfeeding 7. Patients who have undergone periodontal treatment within the last 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical Periodontal Parameter-Gingival Index (GI) | Baseline-4 weeks | Improvement in GI (lower scores mean a better outcome)Minimum score:0 Max.score:3 |
| Clinical Periodontal Parameter-Papillary Bleeding Index (PBI) | Baseline-4 weeks | Improvement in PBI (lower scores mean a better outcome)Minimum score:0 Max.score:4 |
| Clinical Periodontal Parameter-Plaque Index(PI) | Baseline-4 weeks | Improvement in PI (lower scores mean a better outcome)Minimum score:0 Max.score:5 |
Countries
Turkey (Türkiye)
Outcome results
None listed