Hair Fragility, Nails, Ingrown, Skin Condition
Conditions
Keywords
fish collagen
Brief summary
To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human
Interventions
DIETARY_SUPPLEMENTMarine Collagen Peptides
consume 1 bottle per day
DIETARY_SUPPLEMENTplacebo drink
consume 1 bottle per day
Sponsors
TCI Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Healthy adults aged above 18 years old
Exclusion criteria
* Subjects who are not volunteers * Subjects who have been diagnosed with dermatitis, cirrhosis, and chronic kidney failure * Subjects who have known cosmetic, drug or food allergies. * Patients are taking medicine for chronic diseases * Subjects receiving treatments for scalp, hair transplant, and other scalp medical care in past 12 weeks. * Subjects getting a manicure and perm in past 12 weeks. * Female who is pregnant or nursing or planning to become pregnant during the course of the study. * Subjects receiving facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 12 weeks. * Students who are currently taking courses taught by the principal investigator of this trial. * Subjects are not willing to reveal the results of pictures after taking the product * Vegetarian.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The degree of nails fragility | Change from Baseline nails fragility at 12 weeks | Iron ruler was utilized to evaluate nails fragility. Picture taken was utilized to record and observe the change of nails fragility. |
| The change of skin hydation | Change from Baseline skin skin hydation at 12 weeks | Corneometer® CM825 (CK, Germany) was utilized to measure skin surface hydation. Units: arbitrary Corneometer® units 0-120. |
| The change of skin wrinkles | Change from Baseline skin wrinkles at 12 weeks | VISIA Complexion Analysis was utilized to measure skin wrinkles. Units: the amount of detectable wrinkles |
| The change of skin elasticity | Change from Baseline skin elasticity at 12 weeks | Cutometer® MPA580 was utilized to measure skin elasticity. Units: visco-elasticity in %. |
| The change of skin collagen density | Change from Baseline skin collagen density at 12 weeks | DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units |
| The change of hair diameters | Change from Baseline hair diameters at 12 weeks | Mitutoyo C/N293-100 was utilized to measure hair diameters. Units: millimeter |
| The change of hair loss amount | Change from Baseline hair loss amount at 12 weeks | Collect and measure the weight of loss hair. Units: gram |
| The change of hair roots diameters | Change from Baseline hair roots diameters at 12 weeks | Mitutoyo C/N293-100 was utilized to measure hair roots diameters. Units: millimeter |
| The change of hair density | Change from Baseline hair density at 12 weeks | Soft Plus was utilized to picture and observe hair density. |
| The change of hair follicle strength | Change from Baseline hair follicle strength at 12 weeks | Pull up the hair of the frontal bone, temporal bone and occipital bone (approximately 60 hairs/area) to assess the number of hair loss in each area. Units: the number of loss hair |
| The change of thumbs nail color | Change from Baseline thumbs nail color at 12 weeks | Chroma Meter MM500 was utilized to measure thumbs nail color. Units: L\* index |
| The change of nails appearence | Change from Baseline nails appearence at 12 weeks | Picture taken was utilized to record and observe nails appearence. |
| The change of nails growth | Change from Baseline marking position at 12 weeks | Marking the position of middle fingers lunula was utilized to record and observe nails growth. Units: milimeter |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The change of self-assessment skin, hair, and nails condition | Change from Baseline skin, hair, and nails condition at 12 weeks | A self-assessment questionnaire was collected and evaluate skin, hair, and nails condition |
Countries
Taiwan
Outcome results
None listed