PCO, Polycystic Ovary Syndrome
Conditions
Keywords
PCO, Polycystic Ovary syndrome, Females, Body Image concerns
Brief summary
The goal of this randomized controlled trial is to compare the effects of High intensity circuit training, Intermittent Fasting, and their combination on PCOS morphology, Anthropometrics, clinical hyperandrogenism and body image concerns in females with PCOS. Participants will be divided into three groups who will receive High intensity circuit training, Intermittent fasting and their combination. The outcomes will be PCOS morphology, anthropometrics', clinical hyperandrogenism and body image concerns.
Interventions
High Intensity circuit training consisting of circuits of high intensity exercises and progressed up to 8 weeks will be provided.
Time restricted feeding will be used in which the intervention will begin with a 12:12 window leading to a 16:8 IF protocol.
OTHERCombination of HICT and IF
The participants will follow both HICT and IF for 8 weeks.
Sponsors
Riphah International University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
* Unmarried females * Diagnosed with PCOS Phenotype A based on Rotterdam Criteria: * PCOM on US * Ovulatory dysfunction * Clinical Hyperandrogenism (Hirsutism modified Ferriman Gallway score ≥ 8) * Not engaged in any regular lifestyle intervention for <3 Months prior to inclusion
Exclusion criteria
* Use of Estrogen, Progestin or combination. * Taking medications or supplements for Insulin resistance < 3 months prior to the inclusion * Type I or II DM * Hypo/hyperthyroidism * BMI ≥27 (Obese according to BMI Asia)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| PCOS Morphology | 8th Week | Changes from baseline PCOS morphology on the ultrasound will be done by calculating the number of follicles and measuring follicle size. For this purpose, ultrasound imaging is the best option as it is both harmless and inexpensive. PCOS is considered if on ultrasound imaging there are 12 or more than 12 follicles in the ovary and has size of 2-9 mm or volume of 10 cm 3 . |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Anthropometrics | 8th Week | Changes from baseline Weight (kg) will be measured by weight scale while height (ft) will be measured by stadiometer. BMI will be calculated by dividing your weight in kilograms (kg) by your height in meters squared (m 2 ). Waist Circumference (WC) will be measured in centimeters, between the costal margin and the pelvic brim, and Hip Circumference (HC) will be measured in cm at the level of the symphysis pubis by inches tape. |
| Clinical Hyperandrogenism | 8th Week | Changes from baseline Modified Ferriman Gallwey (mFG) score will be used to assess the hirsutism as a measure of clinical hyperandrogenism. |
| Body Image concerns | 8th Week | Changes from baseline Body Image concerns will be measured using The BSQ which is a self-reported measurement of the body shape concerns designed for women to measure concerns about body image problems. |
Countries
Pakistan
Contacts
Primary ContactImran Amjad, PhD
Outcome results
None listed