Outcomes and Risk Factors of CPR in PICU

Outcome of Cardiopulmonary Resuscitation in Tertiary Level PICU and Associated Risk Factors

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06300710

Enrollment

Registered

2024-03-08

Start date

2024-08-01

Completion date

2025-03-01

Last updated

2024-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardio Respiratory Arrest

Brief summary

1. To detect the frequency and the underlying causes of cardiopulmonary arrest . 2. To detect outcome of CPR 3. To identify the associated risk factors for the different outcomes after CPR among those patients

Detailed description

Cardiac arrest (CA) is uncommon in children, and the epidemiology of pediatric CA is different from adults. CA Is a critical cause of death in children in the hospital especially in the pediatric Intensive care unit (PICU). CA Is reported in 2-6% of children in the PICU, which is much higher than out-of-hospital arrest (about 8 to 20 annual cases per 100,000 pediatric population . Previous studies reported that return of spontaneous circulation (ROSC) after cardiopulmonary Resuscitation (CPR) for in-hospital CA (IHCA) is about half of these patients, and ∼30% survived to hospital discharge Previous studies had analyzed the cause and prognostic factors associated with outcomes after IHCA, which included the Initial rhythm, duration of CA and CPR, the underlying disease, and where the event attacked . Patients in PICU are more likely to develop CA because they are more critically ill. Information on factors associated with prognosis of in-PICU CA can promote Improvement in PICU care, which means improving survival with good neurologic outcomes . Analyzing the epidemiological variables and risk/prognostic factors of in-PICU CA is of great Importance in developing the better therapeutic strategy and deciding appropriate preventive Measure . Probability of death on admission and a longer length Of stay in the PICU were associated with increased odds of receiving CPR. Children admitted with cardiac conditions were at significantly higher risk of receiving CPR in the PICU Compared with those Admitted with noncardiac primary diagnosis. The risk Of receiving CPR was significantly associated with age, History of preadmission CPR, also, Electrolyte Imbalances and Multi-organ Dysfunction increase risk of receiving CPR in PICU .

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Months to 18 Years

Healthy volunteers

Yes

Inclusion criteria

* Including Children aged 1 month to 18 years who received at least 1 minute of CPR

Exclusion criteria

* Exclusion of 1-Children aged below1 month and older than 18 years . * terminal disease patients, such as malignancy

Design outcomes

Primary

Measure	Time frame	Description
incidence of cardiac arrest and survival to discharge from the PICU (dead versus alive)	1 year	(dead versus alive)

Secondary

Measure	Time frame	Description
Rate of risk factors associated with outcome of CPR	1 year	Rate of the risk factors associated with the outcome of CPR.

Contacts

Primary ContactEman HK Khalaf, Resident physician

emanh.khalaf1911@yahoo.com+201111452811

Backup ContactZeinab Mohamed Mohieldeen, Professor

zeinabmohieldeen1993@aun.edu.eg01149913112

Outcome results