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Risk Factors for Acute Kidney Injury in Patients Undergoing Arthroplasty

Risk Factors for Acute Kidney Injury in Patients Undergoing Total Joint Arthroplasty

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06296108
Enrollment
911
Registered
2024-03-06
Start date
2022-06-01
Completion date
2022-12-31
Last updated
2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arthroplasty, Postoperative Acute Kidney Injury

Keywords

arthroplasty, acute kidney injury

Brief summary

The authors aimed to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty.

Detailed description

Aim: The primary aim of the current study is to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty. Considering that this patient group is mostly composed of advanced age and comorbid patients, the secondary aim of the study is to identify risky patients with predictable risk factors and to chart a way to make preoperative optimizations of the patients before developing postoperative complications. Materials and Methods: Patients who underwent joint arthroplasty between 2015 and 2020 in Ankara University Faculty of Medicine, Department of Orthopedics and Traumatology were included. Within the scope of the study, patients' gender, age, weight, height, body mass index values, smoking, American Society of Anesthesiologist (ASA) score, Charlson-Comorbidity Index score (CCI), type of operation, duration of surgery, presence of intraoperative hypotension, anesthesia method , diabetes, hypertension, coronary artery disease, presence of congestive heart failure, presence of preoperative anemia, preoperative uric acid and albumin level, use of nephrotoxic agents in the perioperative period, basal creatinine and glomerular filtration rate (GFR) values, platelet suspension in the perioperative period, erythrocyte suspension, Amounts of fresh frozen plasma transfusions, postoperative creatinine at 24 hours - 48 hours - discharge, GFR values and Kidney Disesae Improving Global Outcomes (KDIGO) scores, length of hospital stay and length of stay in the intensive care unit were evaluated.

Interventions

OTHERacute kidney injury

The incidence of acute kidney injury was determined in patients included to the study

Sponsors

Ankara University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients aged above 18 years old undergoing arthroplasty surgery

Exclusion criteria

* Known acute renal failure or chronic renal failure * Patients aged below 18 years old * Patients refusing to participate to the study

Design outcomes

Primary

MeasureTime frameDescription
Acute kidney injury in patients undergoing arthroplasty surgeryRetrospective between 2015-2020To determine the incidence of acute kidney injury in patients undergoing arthroplasty surgery

Secondary

MeasureTime frameDescription
Risk factors causing acute kidney injury in patients undergoing arthroplasty surgeryRetrospective between 2015-2020To determine the risk factors causing acute kidney injury in patients undergoing arthroplasty surgery

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026