Dental Implant
Conditions
Keywords
dental implant, Subepithelial Connective Tissue Graft, Amniotic Chorion Membrane, for Peri-implant Mucosa
Brief summary
The objective of this study will be to assess the efficacy of the peri-implant mucosal thickness enhancement following either subepithelial connective tissue grafts or Amnion Chorion Membrane placed simultaneously with dental implant placement.
Interventions
PROCEDUREimplant placement and soft tissue augmentation with Autogenous Subepithelial Connective Tissue Graft or Amniotic Chorion Membrane
assess the efficacy of the peri-implant mucosal thickness enhancement following either subepithelial connective tissue grafts or Amniotic Chorion Membrane placed simultaneously with dental implant placement.
Sponsors
Tanta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
30 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* Patients with good systemic health with no contraindication for periodontal surgery. * No history of any medications in the previous 6 months that may interfere with periodontal tissue health or healing. * Ability to maintain good oral hygiene as evidenced in recall visits. * Aged 30 to 55 years. * Stable periodontal condition and missing one single tooth (maxillary anterior teeth and premolars) with adjacent teeth present and thin mucosal phenotype (\< 2mm bucco- lingual thickness).
Exclusion criteria
* Medically compromised patients and systemic conditions precluding periodontal surgery. * Smokers. * Severe hematologic disorders (e.g., hemophilia or leukemia), uncontrolled infectious or metabolic diseases that could compromise normal healing, liver, or kidney dysfunction/failure. * Patients subjected to irradiation in the head and neck area. * Patients treated or under treatment with intravenous amino bisphosphonates. * Patient affected by active periodontitis or has poor oral hygiene and motivation. * Uncontrolled diabetes mellitus. * Pregnant women or planning become pregnant, and nursing mothers.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measure changes in periimplant mucosal thickness | six months | The primary outcome of interest will be to measure changes (in mm) in horizontal periimplant mucosal thicknesson the buccal aspect of the edentulous alveolar ridge from baseline (BL) (implant placement and grafting) to (3 and 6 month) of post-surgical healing. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| mid-buccal keratinized mucosal width | six month | measure change (in mm) in mid-buccal keratinized mucosal width in an apico-coronal direction |
Countries
Egypt
Contacts
Primary Contactahmed a abdelsayed
Outcome results
None listed