Comparison Between Bupivacaine-Dexmedetomidine Versus Bupivacaine-Dexamethasone in Pericapsular Nerve Group (PENG) Block

Comparison Between Bupivacaine-Dexmedetomidine Versus Bupivacaine-Dexamethasone in Pericapsular Nerve Group (PENG) Block as Post-operative Analgesia in Hip Surgeries.

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06294665

Enrollment

Registered

2024-03-05

Start date

2024-03-01

Completion date

2025-01-01

Last updated

2024-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Fractures, Post Operative Pain

Brief summary

The aim of this work is to compare the effectiveness of bupivacaine- dexmedetomidine mixture versus bupivacaine-dexamethasone mixture in PENG Block as Post-operative Analgesia in Hip surgeries

Interventions

DRUGPericapsular Nerve Group (PENG) Block

The PENG block will be performed ,the patient is placed in the supine position , the procedural leg is slightly abducted, the curvilinear low-frequency ultrasound probe will be placed over the line parallel to the inguinal ligament. It will subsequently rotated 45◦ to identify the anterior inferior iliac spine, the iliopubic eminence, and the psoas tendon. A 22-gauge, 80 mm echogenic needle will inserted in an in-plane approach to place the tip in the musculofascial plane between the pubic ramus posteriorly and the psoas tendon anteriorly. Following negative aspiration, by one of the two syringes each one has a serial number corresponding to each group.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

1. Age 18-65 years. 2. Sex: Both sexes. 3. American Society of Anaesthesiologists (ASA) Physical Status Class I and II. 4. Scheduled for hip surgeries under spinal anaesthesia.

Exclusion criteria

1. Declining to give written informed consent. 2. History of allergy to the medications used in the study. 3. Contraindications to regional anesthesia (including patient refusal, coagulopathy and local infection). 4. Psychiatric disorder. 5. American Society of Anesthesiologists (ASA) Physical Status Class III and IV.

Design outcomes

Primary

Measure	Time frame	Description
The time to the first request of analgesia	9 months	The time interval between the onset of the local infiltration done at the end of the operation and the first request to postoperative analgesia.

Secondary

Measure	Time frame
Total doses of analgesia (Nalbuphine) given to patients in 24 hours postoperatively	9 months
Occurrence of side effects of drugs.	9 months

Countries

Egypt

Contacts

Primary ContactMohamed AA Salama

m_adel92@hotmail.com+201006206630

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026