Noise; Adverse Effect, Noise Exposure
Conditions
Brief summary
Environmental noise represents a health problem for at least one in five citizens of the European Union. Noise exposure leads to the development of arterial hypertension, myocardial infarction, stroke, and obesity. Given the limited information on noise exposure and noise effects on humans in the Republic of Serbia, the overall objective of NOXYCARD is to collect environmental noise levels data; to identify long-term and short-term noise effects on the cardiovascular system; and to evaluate the levels of blood stress hormones, oxidative stress, and inflammation in individuals with normal body weight and individuals with obesity.
Interventions
OTHERExposure to loud pre-recorded road traffic noise
Participants of both arms will be exposed to the same loud pre-recorded road traffic noise in a laboratory setting.
Sponsors
University of Belgrade
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* age 18-65 * both genders * good self-reported health
Exclusion criteria
* diabetes mellitus * arterial hypertension or other cardiovascular diseases * kidney diseases * pregnancy * malignant diseases * mental diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Systolic blood pressure | 10, 40, and 50 minutes | Systolic blood pressure in mmHg, higher values indicate high risk |
| Concentration of stress hormone | 10, 40, and 50 minutes | Cortisol level in mcg/dL, higher values indicate high risk |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Concentration of inflammation parameters | 10, 40, and 50 minutes | Interleukin-1-Beta levels in pg/mL, higher values indicate high risk |
| Diastolic blood pressure | 10, 40, and 50 minutes | Diastolic blood pressure in mmHg, higher values indicate high risk |
Countries
Serbia
Contacts
Primary ContactBranko Jakovljevic, MD, PhD
Outcome results
None listed