Enlarged Pores
Conditions
Brief summary
The purpose of this study is to assess the efficacy and safety of microneedle patch with botulinum toxin for improving enlarged pores.
Interventions
DEVICEMicroneedle patch
with 20 units botulinum toxin
DEVICEIntradermal injection
with 20 units botulinum toxin
Sponsors
Dhurakij Pundit University
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* At least 18 years old and concerned about enlarged pores * Have pore size 0.3-0.6 mm * Have pore parameter in each other side of faces not different more than 5%
Exclusion criteria
* Any neuromuscular condition * Pregnancy or breast feeding * History of allergy : Botulinum toxin, topical anesthesia * History of keloid or hypertrophic scar * History of coagulation or receiving medication that causes coagulation disorder * Using drugs that have interaction with Botulinum toxin * Using topical medication that improves enlarged pores in 1 month * Taking medication that improves enlarged pores in 1 month * Receiving the laser/treatment/chemical peeling in 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline of enlarged pores as measured by VISIA (pores parameter) and using pore score | Post-intervention, week 4 and week 16 | the used pore scores, patients with visible pores took the score 1, and those with enlarged pores took 2. When black heads were embedded on facial pores the score was 3. The scores were assessed by 2 investigators who were blinded to the treatment used on each side. |
Countries
Thailand
Outcome results
None listed