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Effects of HIIT on Muscle Strength, Atrophy and Aerobic Capacity in Stroke Patients.

Effects of High-Intensity Interval Training on Muscle Strength, Atrophy and Aerobic Capacity in Stroke Patients.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06292442
Enrollment
34
Registered
2024-03-05
Start date
2023-09-01
Completion date
2023-11-01
Last updated
2024-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Keywords

aerobic capacity, chronic stroke, high-intensity interval training, muscle atrophy, muscle strength, stroke

Brief summary

To determine the effects of High-Intensity Interval Training on muscle strength, atrophy, and aerobic capacity in stroke patients.

Interventions

OTHERtraditional physical therapy

This group received conventional physical therapy treatment including Range of Motion (ROM) exercises for the affected hip, knee, and ankle joints, as well as stretching exercises for tight lower limb muscles, administered 3 times per week for 4 weeks, with each session lasting approximately 20-30 minutes.

OTHERHigh intensity interval training

This group received High Intensity interval training along with conventional treatment for lower limb muscles, performed 3 times per week fr 4 weeks.

Sponsors

Riphah International University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
40 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Both males and females were included * aged 40-60 years * Chronic stroke patients who experienced a first-ever ischemic stroke * Stable cardiovascular condition (American Heart Association class B) * Physician clearance to participate in a 4-week HIIT program * No prior structured exercise in the last 3 months * Ability to walk 10 m over ground with or without assistive devices * Patients who scored \>24/30 on MMSE (Mini-Mental State Examination)

Exclusion criteria

* Patients who were hospitalized for cardiac or pulmonary disease within the past 3 months * Patients who had implanted pacemaker or defibrillator * Patients having conditions where VO2peak assessment is contraindicated, such as uncontrolled hypertension(\>180/100), severe aortic stenosis, acute myocarditis, recent myocardial infarction, or other acute cardiovascular events within the past three months, were excluded from the study * Patients with severe lower limb spasticity (Ashworth Scale scores \>2 of 4 for knee flexion, knee extension, or ankle dorsiflexion) * Pregnant females * Previous exposure to fast treadmill walking in the past year

Design outcomes

Primary

MeasureTime frameDescription
Muscle strength4th weekManual Muscle Testing is a test that is used to assess muscle strength.
Muscle Atrophy4th weekMeasuring tape is used to measure the calf circumference to measure the atrophy, muscle size over time.
6-Minute Walk Test (6MWT)4th week6-Minute Walk Test (6MWT) used to measure Functional capacity, aerobic fitness and endurance.
Aerobic Capacity4th weekHarvard Step Test is used to measure Functional capacity, aerobic fitness and endurance.

Secondary

MeasureTime frameDescription
Fastest Gait Speed4th week10-Meter Walk Test is a test used for assessing gait speed, monitoring rehabilitation progress, functional assessment, fall risk assessment, and research purposes.

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026