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Study of Multifrequential Impedancemetry in Pulsatile Tinnitus

Study of Multifrequential Impedancemetry in Pulsatile Tinnitus

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06290999
Acronym
MADMAN
Enrollment
36
Registered
2024-03-04
Start date
2024-06-03
Completion date
2025-09-04
Last updated
2026-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulsatile Tinnitus

Keywords

Pulsatile Tinnitus, multifrequency admittancemetry

Brief summary

This study intended to search for a relationship between the multifrequential admittancemetry and the pulsatile tinnitus.

Detailed description

The multifrequency admittancemetry is known to reflect several parameters of the middle ear and the external ear. More recently it appears to also reflect some parameters of the inner ear, such as the perilymph pressure. Furthermore, investigators do not know exactly the physiopathology of pulsatile tinnitus that are from veinous etiology. Modifications of the perilymphatic pressure could be implicated. Investigators intended to search for a relationship between these both theories. Investigators will include every patient that consult to Ear, Nose and Throat unit of Bordeaux University Hospital with a pulsatile tinnitus trouble, and perform multifrequential admittancemetry. If a radio-surgical intervention is scheduled for a venous stenosis, the test will also be performed test after the surgery. If there is no surgical intervention, no follow-up will be required.

Interventions

DIAGNOSTIC_TESTmultifrequential admittancemetry

Every participant of the study have to complete an Ear, Nose and Throat examination included a conventional audiometry, and a multifrequential admittancemetry. if radio-interventional venous stenting is not indicated, an multifrequential admittancemetry will also be performed 3 months after the procedure.

Sponsors

University Hospital, Bordeaux
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult patient * Unilateral or bilateral pulsatile tinnitus * Pulsatile tinnitus \> 1 month old * Affiliated or beneficiary of by social security system

Exclusion criteria

* Otological surgery, excluding trans-tympanic aerators in childhood with closed eardrum * Middle ear abnormality (any type of partial or total filling of the middle ear) noted on otoscopy or subsequent MRI scan * Abnormal eardrums excluding tympanosclerosis * Non-pulsatile tinnitus * Conductive hearing loss with abolition of stapedial reflexes * Minor patient * Major protected * Abnormal tympanometry at 226 Hz * Presence of rotatory vertigo * Opposition to participation expressed by patient

Design outcomes

Primary

MeasureTime frameDescription
Multifrequency admittancemetryAt Day 0 (inclusion)G conductance peak width at 2000 Hz

Secondary

MeasureTime frameDescription
compression maneuversAt Day 0 (inclusion)Evaluation of the effect of compression maneuvers on the width of the G 2000 peak of the IMF in venous or arterial pulsatile tinnitus, whether or not the maneuver is effective.
Evaluation of the effect of interventional radiologyup to 3 month after inclusion (M3)Evaluation of the effect of interventional radiology procedures such as transverse sinus stenting on MFI values.
success of radiointerventional treatmentup to 3 month after inclusion (M3)Search for a predictive factor of success of radiointerventional treatment of venous pulsatile tinnitus: search for a threshold value of pre-operative G2000, separating two groups: success and non-success (groups defined by a THI (Tinnitus Handicap Index) divided by 2 in the success group).

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 7, 2026