Infertility
Conditions
Brief summary
Poor responders in in-vitro fertilization (IVF) cycles represent a major challenge for fertility specialists. Although poor responders tend to have sub-optimal fertility treatment outcomes, many of these patients wish to attempt at least one IVF cycle. Traditionally, IVF cycles producing less than 3 to 4 mature follicles (measuring at least 14 mm) have either been cancelled or converted to intra-uterine insemination (IUI) due to the low pregnancy rates associated with these cycles. The minimal number of follicles required to proceed with egg collection is based on clinical experience, having been determined by weighing the probability of implantation and pregnancy versus the risk of not obtaining quality oocytes or reaching embryo transfer when fewer mature follicles are present. This retrospective quality control study aims to compare pregnancy rates in IVF cycles producing 3 follicles measuring 14 mm and more on trigger day, versus 2 or fewer follicles.
Interventions
OTHEROvulation triggering
Ovulation triggering when women only 2 dominant follicles as opposed to the clinic's standard of 3 follicles or more
Sponsors
Clinique Ovo
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 42 Years
Healthy volunteers
No
Inclusion criteria
* Stimulated IVF cycle at clinique ovo * Patients with a maximum of 3 mature follicles (≥14mm) on the day of ovulation trigger
Exclusion criteria
* Cycle cancelation due to no follicles * History of recurrent implantation failure * Contraindication of ovulation induction medication
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical Pregnancy Rate | 6 to 8 weeks after Frozen Embryo Transfer | clinical pregnancy is the presence of fetal heartbeat at the viability ultrasound |
Countries
Canada
Outcome results
None listed