Cognitive Decline
Conditions
Brief summary
The main objective of this project is two-fold 1. to develop a Dual-Task training exploiting the potentiality of the 360° technology in terms of interactivity and ecological validity 2. to investigate its efficacy in improving the cognitive functioning in a randomized clinical trial for 2 different populations: subjects with subjective memory complaints and mild cognitive impairment. Specifically, participants will follow an integrated training including 2 phases: 1)in-hospital rehabilitation, where subjects will be provided sessions of the training in immersive modality; 2)at-home rehabilitation, where older adults will be asked to perform at home the non-immersive version of the training using a tablet. Expected outcome is an improvement in cognitive functioning (assessed with a complete neuropsychological battery) after the training, thus advancing literature about non-pharmacological interventions in the preclinical stages of dementia along with innovative technical instruments.
Interventions
DEVICE360° media
sessions with head mounted display in hospital and sessions with tablet at home
OTHERTreatment As Usual (TAU)
sessions of TAU rehabilitation in hospital and sessions TAU rehabilitation at home
OTHERIn hospital sessions
sessions will be carried out under the supervision of a therapist
OTHERat home sessions
sessions will be carried out without the supervision of a therapist
OTHERMild Cognitive Impairment
half of this group will perform the protocol with 360° videos and the other half will perform the TAU
OTHERSubjective Memory Complain
half of this group will perform the protocol with 360° videos and the other half will perform the TAU
Sponsors
Istituto Auxologico Italiano
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
DOUBLE (Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
(group of SMC): * \> 65 years old * self-reported memory complaints * score on Mini-Mental State Examination greater than or equal to 27/30 (normal range)
Exclusion criteria
* no evidence of objective impairments on the neuropsychological testing, scores on the Clinical Dementia Rating \< 0.5 Inclusion Criteria (group of MCI): * \> 65 years old * a self-reported (or reported by a caregiver) cognitive decline * an objective impairment on the neuropsychological testing * scores on the Clinical Dementia Rating \< 0.5.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cognitive functions | Immediately after the training experience | Improvement in cognitive functioning assessed with a complete neuropsychological battery focused on different domains such as executive function, memory, and attention. |
| Motor functions | Immediately after the training experience | Improvement in motor functioning assessed with specific test focused on balance, functional mobility, and walking speed |
Countries
Italy
Contacts
Primary ContactElisa Pedroli, PsyD
Outcome results
None listed