Cesarean Section, Postanesthetic Excitement
Conditions
Keywords
shivering, dexmedetomidine, ondansetron, regional anesthesia
Brief summary
Evaluate the efficiency of management with intravenous dexmedetomidine compared to intravenous ondansetron to achieve the disappearance of post-anesthetic shivering in a shorter time in the obstetric patient undergoing cesarean section under regional anesthesia.
Detailed description
Randomized clinical trial with 40 pregnant patients, between 18 and 45 years old with ASA (American Society of Anesthesiologist) II or III, undergoing scheduled or emergency cesarean section with regional anesthesia and who presented grade tremor 1 based on the BSAS (Bedside shivering assessment scale) scale, at the Hospital Central from San Luis Potosi, Mexico. The main objective of this study was to quantify the time that elapsed from the end of the administration of the medication until the disappearance of the tremor, which was measured in minutes; The evaluation of the disappearance, persistence or reappearance of the tremor was solely visual by the anesthesiology staff.
Interventions
DRUGsaline solution
20 mL of saline
Sponsors
Hospital Central Dr. Ignacio Morones Prieto
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* ASA II or III, undergoing scheduled or emergency cesarean section with regional anesthesia (hyperbaric bupivacaine 0.5% with morphine at 1 mcg Kg-1) and who presented tremor grade \>1 based on the BSAS scale
Exclusion criteria
* Hemodynamic instability, heart disease or sinus bradycardia, allergy to any of the medications applied, psychiatric diseases or hypothermia \<35.2 ºC measured by tympanic temperature.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Period of time | one hour | period of time in which post-anesthetic tremor is controlled from the moment of administration |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adverse effects | one hour | To measure the frequencies of occurrence of adverse effects and changes in vital signs (heart rate, blood pressure, and temperature \[measured at the tympanic membrane\]) correlated with resolution of tremor. |
Countries
Mexico
Outcome results
None listed