Severe Acute Respiratory Syndrome
Conditions
Keywords
Prone, Lung protective, ARDS, APACHI II, SOFA
Brief summary
Background and objective: The ramifications of early lung protective measures and prone positioning on the ICU length of stay rates of participants admitted to the ICU with acute respiratory distress syndrome amid the COVID-19 pandemic constitute a pivotal examination. The study aims to identify the effect of early prone positioning on the length of stay, discharge rate, and number of tracheostomized patients in the ICU.
Detailed description
Background and objective: The ramifications of early lung protective measures and prone positioning on the ICU length of stay rates of participants admitted to the ICU with acute respiratory distress syndrome amid the COVID-19 pandemic constitute a pivotal examination. The study aims to identify the effect of early prone positioning on the length of stay, discharge rate, and number of tracheostomized patients in the ICU. Methodology: This retrospective study was conducted on critically ill patients needing mechanical ventilation with lung protective strategy and admitted to the Intensive Care Units of Al-Azhar University Hospitals between March 2020 to April 2022. All patients in the study were interpreted retrospectively by examining the patient's records. Group A (n:39) included patients who had been early placed in prone positions within 24 hours of intubation, and Group B (n:31) included patients who had not been placed in prone positions. All patients received a lung protective strategy for ARDS. In both groups, PaO2, PaCo2, PH, SpO2, and PaO2/FiO2 ratio were checked initially and later every 24 hours for 6 days. All patients were evaluated for the total days of both hospital and ICU length of stay, number of successful discharges to home from the hospital, and the total number of tracheostomized patients.
Interventions
OTHERPRONE POSITION
early placed in prone positions within 24 hours of intubation
Sponsors
Al-Azhar University
Zulekha Hospitals
Study design
Observational model
CASE_CONTROL
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* All patients of both sexes. * Aged from 18 to 70 years. * Body Mass Index (BMI) from 25 to 35 kg/m2. * Critically ill due to ARDS resulting from COVID-19 pneumonia.
Exclusion criteria
* Patients who spent more than 24 hours on mechanical ventilators before enrolment in the study. * Patients who died within the first 24 hours of presentation. * Patients with advanced cancer. * Pregnant patients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of discharged patients | 26 MONTHS | Number of discharged patients |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The total length of stay | 26 MONTHS | The total length of stay |
| ICU length of stay | 26 MONTHS | ICU length of stay |
| Patients who underwent tracheostomy procedures | 26 MONTHS | Patients who underwent tracheostomy procedures |
Countries
Egypt
Outcome results
None listed