Abdominal Bloating, Abdominal Distention
Conditions
Keywords
abdominal distention, small intestinal bacterial overgrowth, orocecal transit time, cross-sectional survey, abdominal bloating
Brief summary
Abdominal bloating/distention represents a prevalent clinical manifestation characterized by an unclear etiology and pathogenesis. This symptomatology is frequently observed in various conditions, including small intestinal bacterial overgrowth (SIBO). The utilization of the breath test as a non-invasive diagnostic approach has become widespread in recent years for identifying SIBO. In this study, the prevalence of SIBO irregularities in individuals presenting with abdominal bloating/distention was ascertained through the implementation of the breath test. Furthermore, the correlation between abdominal bloating/distention and SIBO was analysed to enhance the elucidation of the underlying etiology of abdominal bloating/distention. These findings aim to offer valuable insights for refining clinical comprehension and strategies related to the diagnosis and treatment of abdominal bloating/distention.
Detailed description
Abdominal bloating/distention represents a prevalent clinical manifestation characterized by an unclear etiology and pathogenesis. And the prevalence of Abdominal bloating/distention represents a prevalent clinical manifestation characterized by an unclear etiology and pathogenesis. This symptomatology is frequently observed in various conditions, including small intestinal bacterial overgrowth (SIBO). The utilization of the breath test as a non-invasive diagnostic approach has become widespread in recent years for identifying SIBO. In this study, the prevalence of SIBO irregularities in individuals presenting with abdominal bloating/distention was ascertained through the implementation of the breath test. Furthermore, the correlation between abdominal bloating/distention and SIBO was analysed to enhance the elucidation of the underlying etiology of abdominal bloating/distention. These findings aim to offer valuable insights for refining clinical comprehension and strategies related to the diagnosis and treatment of abdominal bloating/distention.
Interventions
DIAGNOSTIC_TESTBreath test
The concentration of methane and hydrogen in the exhaled gas of patients with Abdominal bloating/distention is measured by a breath test to determine the presence of SIBO.
Sponsors
Shandong University
Jinan Central Hospital
Zaozhuang Municipal Hospital
Weifang People's Hospital
Dezhou Hospital Qilu Hospital of Shandong University
Binzhou Medical University
Qihe Xian Renmin Hospital
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
1. Patients aged 18 to 70 years. 2. Patients presenting with the primary complaint of abdominal bloating and/or abdominal distension, or those exhibiting abdominal distension with prominence over other symptoms.
Exclusion criteria
1. Patients who are pregnant or lactating. 2. Patients have history of gastrointestinal malignancy or gastrointestinal surgery. 3. Patients manifesting food intolerance or presenting with a confirmed diagnosis or suspicion of lactose intolerance. 4. Patients with urinary system (chronic kidney disease, etc.), immune system (scleroderma, etc.), nervous system (Parkinson's disease, etc.), mental system (depression, etc.), or other diseases outside the digestive system. 5. Patients who used antibiotics or microecological agents or underwent endoscopic examination within two weeks. 6. Patients with a medication history encompassing motility enhancers, secretory enhancers, antifoaming agents, spasmolytics, opioids, and antidepressants within the past week. 7. Patients who are unwilling or incapable to provide informed consents.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Positive rate of SIBO in patients with abdominal bloating/distension | 2024-03-01 to 2026-06-01 | Detect the positive rate of SIBO in patients with abdominal bloating/distension by breath test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between clinical features of patients with abdominal bloating/distension and SIBO | 2024-03-01 to 2026-06-01 | Analyze the correlation between clinical features of patients with abdominal bloating/distension and SIBO |
Countries
China
Contacts
PRINCIPAL_INVESTIGATORFeixue Chen, MD
Qilu Hospital of Shandong University
Outcome results
None listed