Anthropometry, Cardiorespiratory Fitness, Metabolism
Conditions
Brief summary
The aim of this study is to investigate whether there are the additive effects when implementing both high-intensity interval training (HIIT) and probiotics simultaneously on improving cardiorespiratory endurance and metabolism in middle-aged women.
Detailed description
High-intensity interval training (HIIT) is a time-efficiency exercise mode that has been shown to reduce body fat, fasting blood insulin levels, arterial stiffness, and aerobic capacity, helping to prevent and improve chronic diseases. Probiotics, on the other hand, have been found to have similar effects, including improving insulin sensitivity and endurance exercise performance, as well as reducing body fat. However, the additive effects of HIIT combined with probiotic supplements are unclear. In addition, on average, the life expectancy of women is longer than that of men. Middle-aged women are at high-risk for obesity and metabolic-related problems that threaten their long-term health. Therefore, whether the combination of HIIT and probiotics can be utilized to enhance the wellness of middle-aged women is the objective of this study.
Interventions
DIETARY_SUPPLEMENTProbiotics supplementation
Probiotics, Lactiplantibacillus plantarum TWK10, are packaged in powder form. Each participant consume one packet every day on a fasting status for 8 weeks.
BEHAVIORALHIIT training
HIIT training is conduct at the intensity of 85-90% VO2max for 2 minutes with 1-minute inactive resting interval, repeating for 7 times. 3 sessions per week for 8 weeks.
DIETARY_SUPPLEMENTPlacebo supplementation
Yeast powder replaces probiotics in each packet. Each participant consume one packet every day on a fasting status for 8 weeks.
Sponsors
University of Taipei
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
FEMALE
Age
35 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Female * Age between 35-55 years old * Total body fat percentage greater than 30%
Exclusion criteria
* Male * Participants who were taking probiotics supplementation or antibiotics * Percentage of total body fat less than 30%
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time to exhaustion (TTE) | 8 weeks | TTE in seconds |
| Body fat percentage | 8 weeks | Body fat percentage (%) is measured with Dual-energy X-ray absorptiometry (DEXA) |
| Waist circumference | 8 weeks | Waist circumference in centimeters |
| Hip circumference | 8 weeks | Hip circumference in centimeters |
| Maximum oxygen uptake (VO2max) | 8 weeks | VO2max in ml/min/kg |
| Running economy (RE) | 8 weeks | RE in ml/kg/km |
| Fasting blood glucose (FBG) | 8 weeks | FBG in mg/dL |
| Total cholesterol (TC) | 8 weeks | TC in mg/dL |
| Triglyceride (TG) | 8 weeks | TG in mg/dL |
| High-density lipoprotein cholesterol (HDL-C) | 8 weeks | HDL-C in mg/dL |
| Low-density lipoprotein cholesterol (LDL-C) | 8 weeks | LDL-C in mg/dL |
| Height | 8 weeks | Height in centimeters |
| Body weight | 8 weeks | Weight in kilograms |
| Body mass index (BMI) | 8 weeks | Calculated by: weight (kg)/ height (m\^2) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Fat mass | 8 weeks | Fat mass in kilograms is measured with DEXA |
| Bone mineral density (BMD) | 8 weeks | BMD in g/cm\^2 is measured with DEXA |
| Caloric intake | 8 weeks | Caloric intake in kcal/day |
| Muscle mass | 8 weeks | Muscle mass in kilograms is measured with DEXA |
Countries
Taiwan
Outcome results
None listed